Donald L. Lamm, MD, FACS, Director of BCG Oncology and Clinical Professor of Surgery at the University of Arizona College of Medicine, discusses the criteria required of studies looking for alternative drug therapies to Bacillus Calmette-Guerin (BCG) to treat non-muscle invasive bladder cancer (NMIBC). Because there are many BCG refractory, recurrent, intolerant, and unresponsive patients, and because there is a global shortage of BCG, new drugs are much needed. To get funding, studies will require FDA approval, and Dr. Lamm suggests that researchers are more likely to receive approval quickly by using standard definitions and providing clear follow-up and end-points in their proposals.Read More
Donald L. Lamm, MD, FACS
Dr. Lamm is a Clinical Professor of Surgery at the University of Arizona College of Medicine and Director of BCG Oncology, his solo private practice in Phoenix. After completing his undergraduate studies and medical school at the University of California, Los Angeles, he did his urology residency at the University of California, San Diego, with Ben Gittes. The second year of this residency was devoted to research, and it was here that Dr. Lamm’s interest in bladder cancer began. At the suggestion of Dr. Dave McCullough, he added bacillus Calmette-Guérin (BCG) to his animal bladder cancer studies. This led to the first published randomized clinical trial of BCG in 1980, which occurred while Dr. Lamm was at the University of Texas Health, San Antonio. This trial was followed by SWOG comparisons of BCG and doxorubicin, BCG and MMC, and induction versus BCG 3 week maintenance. While Dr. Lamm and others continue looking for new treatments, BCG remains the gold standard in bladder cancer treatment.
Articles by Donald L. Lamm, MD, FACS
Posted by Donald L. Lamm, MD, FACS | Nov 2016
Dr. Donald L. Lamm and Dr. Michael S. Cookson spoke at the 25th annual Perspectives in Urology...Read More