William O. Brant, MD, FACS, FECSM, presented “Guidelines and Practical Applications: Erectile Dysfunction” during the 42nd Annual Ralph E. Hopkins Urology Seminar on February 3, 2023, in Jackson Hole, Wyoming.
How to cite: Brant, William O. “Guidelines and Practical Applications: Erectile Dysfunction.” February 3, 2023. Accessed Feb 2026. https://grandroundsinurology.com/guidelines-and-practical-applications-erectile-dysfunction/
Guidelines and Practical Applications: Erectile Dysfunction – Summary
William O. Brant, MD, FACS, FECSM emphasizes a thorough patient evaluation, including a detailed medical and sexual history, physical examination, and appropriate laboratory tests. He highlights the role of comorbid conditions, such as cardiovascular disease, diabetes, and hormonal imbalances, in the etiology of ED.
Current guidelines recommend a stepwise treatment approach, starting with lifestyle modifications. Dr. Brant discusses the efficacy and safety profiles of first-line pharmacologic therapies, including phosphodiesterase type 5 inhibitors (PDE5is), and their role in different patient populations. He also examines the indications and outcomes of second-line treatments, such as intracavernosal injections and vacuum erection devices, and third-line options, including penile prosthesis implantation.
Dr. Brant provides insights into emerging therapies and future directions in ED management, such as regenerative medicine approaches, including stem cell therapy and platelet-rich plasma injections. He also touches upon the potential of novel pharmacologic agents and the importance of ongoing research in improving patient outcomes.
About The 42nd Annual Ralph E. Hopkins Urology Seminar:
The Ralph E. Hopkins Urology Seminar is a multi-day meeting focused on training urologists in the latest in assessing, diagnosing, and treating urologic conditions in the clinical setting. Updates are provided on urologic cancers, stone disease, urologic reconstruction, female urology, infertility, sexual function, emerging surgical techniques, and general urology. The 42nd iteration of the meeting took place from February 1st to 4th, 2023, in Jackson Hole, Wyoming.
For further educational activities from this conference, visit our collection page.
ABOUT THE AUTHOR
William O. Brant, MD, FACS, FECSM, is the Chief of Urology at the Veterans Affairs Medical Center in Salt Lake City, Utah, and a Urologist with clinical practices at Summit Urology/Granger Medical Clinic in Salt Lake City. His practice is dedicated to men’s health, with a particular focus on sexual and erectile medicine, penile reconstructive surgery, and prosthetic surgery. He has been involved in education, training, and research related to prosthetic surgery, particularly as it relates to prostate cancer survivors, and he performs over 100 prosthetic surgeries annually.
