Topic: Bladder Cancer

En Bloc TURB – More Than a Safe and Feasible Surgical Technique

Salvatore Micali, MD, discusses the pros and cons of en bloc transurethral resection of bladder (TURB) and its advantages over classical TURB. Specifically, he describes how en bloc TURB lends itself to correct specimen orientation, easier identification of the tumor growth front and whether the disease has invaded the chorion, and better determination of the deep surgical margin.

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New Targets for Advanced Bladder Cancer

Daniel P. Petrylak, MD, discusses the efficacy of checkpoint inhibitors in previously cisplatin treated metastatic urothelial carcinoma patients and the need for better biomarkers for checkpoint proteins. He also identifies future directions for treating the disease, including ipilimumab/nivolumab and epacadostat/ pembrolizumab combinations, and PD-L1 immunohistochemical staining.

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