Presentations from the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer

SESSION I (PART 1): PATIENT POPULATION PRIOR TO DIAGNOSIS OF PROSTATE CANCER: SCREENING AND CLINICAL EVALUATION OF MEN WITH CLINICAL SUSPICION

Welcome and Opening Remarks

Faina Shtern, MD, presented opening remarks for the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer.

Advancing Risk-Stratified Screening and Early Detection

Sigrid Carlsson, MD, PhD, MPH, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Update on PROBASE Trial: Baseline PSA in Young Men (Aged 45 and 50)

Peter Albers, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Update on PRAISE-U Project – European Union Initiative in PC Screening

Monique Roobol, PhD, BAO, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Update on Göteborg-2 Trial: PSA Screening Followed by MRI

Jonas Hugosson, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Update on PROSCREEN: A Randomized Population-Based Screening Trial Combining PSA, Kallikrein
Panel and MRI

Anssi Auvinen, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Organized Prostate Testing (OPT) in Sweden

Anders Bjartell, MD, PhD, FEBU, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

TRANSFORM – National UK Trial of Prostate Cancer Screening

Rhian Gabe, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

SESSION I (PART 2): PATIENT POPULATION PRIOR TO DIAGNOSIS OF PROSTATE CANCER: SCREENING AND CLINICAL EVALUATION OF MEN WITH CLINICAL SUSPICION

Overview of Liquid Biomarkers

E. David Crawford, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Large-Scale, Prospective, Clinical Validation Study of the Diagnostic Performance of IsoPSA Without and In Combination with Multi-Parametric MRI for the Detection of High-Grade Prostate Cancer

Mark Stovsky, MD, MBA, FACS, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Micro-Ultrasound-Guided Versus MRI-Guided Biopsy for Prostate Cancer Diagnosis

Laurence Klotz, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

MRI PI-RADS Standardization and Clinical Evaluation

Clare Tempany, MB, BAO, BCh, FACR, FISMRM, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

A Calibration Tool for ADC Measurements in Prostate Cancer

Xavier Golay, PhD, MS, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

State of the Art and Future Directions in Prostate Biopsies: Imaging Perspective

Fergus Coakley, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

State of the Art and Future Directions in Prostate Biopsies: Urological Perspective

Alastair Lamb, MD, PhD, FRCS, CRUK, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Should We Be Preparing for a Biopsy-Free Future?

Mark Emberton, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Current and Emerging Data on the Role of PSMA Imaging in Selecting Patients for Biopsies: Urologic Perspective

Lorenzo Bianchi, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Newly Identified Germline Mutations Associated with Prostate Cancer Risk and Aggressiveness

Brian T. Helfand, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Update of Changes in the Early Detection of Prostate Cancer: NCCN Guidelines for 2025

Preston Sprenkle, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

PANEL ON BIOINFORMATICS, ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING FOR A MULTI-MODALITY DATA ANALYSIS FOR PRECISION DIAGNOSIS AND TREATMENT

Deep Phenotyping of Prostate Cancer via Multi-Model Imaging and AI to Discover High-Risk Phenotypes

Rakesh Shiradkar, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

Augmented Reality for Prostate Biopsies

Archan Khandekar, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

From Silos to Synergy: Data-Driven Strategies in Prostate Cancer Care

Ilya Gipp, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 15, 2025.

SESSION II (PART 1). CLINICAL EVALUATION AND MANAGEMENT OF MEN WITH LOCALIZED AND RECURRENT PROSTATE CANCER

Clinical and Prognostic Implications of Cancer Visibility on Imaging: Radiologic Perspective

Alberto Vargas, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Molecular Imaging

Michael Hofman, MBBS, FRACP, FAANMS, FICIS, FSNNMI, FAHMS, GAICD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Genomics and Natural History of mpMR Visible vs Invisible Cancers: Implications for Clinical Practice

Laurence Klotz, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

PSMA Imaging-Guided Salvage Radiotherapy in Patients with Biochemical Recurrence after Radical Prostatectomy-
Emerging Five-Year Outcomes

Andrea Di Giorgio, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Gleason Pattern 4 Quantification as a Replacement for Gleason Scoring

Andrew Vickers, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Novel and Emerging Pathological Factors in Localized and Recurrent Prostate Cancer

Gladell P. Paner, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Integration of MRI with Histology, Genomics, and Proteomics

Steven Raman, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

SESSION II (PART 2): CLINICAL EVALUATION AND MANAGEMENT OF MEN WITH LOCALIZED AND RECURRENT PROSTATE CANCER

Evaluation & Management of Men with Localized & Recurrent PCa: Next-Generation Risk Stratification

Alastair Lamb, MD, PhD, FRCS, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Old School, New Insight: Histomorphology in the Modern Biomarker Era of Risk Stratification of
Prostate Cancer

Jane Nguyen, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Human-AI Interaction in Prostate Cancer Detection and Diagnosis: Ways to Team Up

Evis Sala, MD, PhD, FRCR, FRCP, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Future Indications of PET PSMA Imaging in Localized Prostate Cancer

Ashley E. Ross, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Integrated Diagnostics for Risk Stratification and Active Surveillance

Sanoj Punnen, MD, MAS, MBA, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Focal Therapy in Prostate Cancer: Ready for Prime Time?

Bruno Nahar, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Focal Brachytherapy for Prostate Cancer

Daniel Y. Song, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Optimal Management of Patients Presenting with Locally Advanced Prostate Cancer in 2025

Raja B. Khauli, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Principles of Focal Salvage Treatment for Radiorecurrent Prostate Cancer: Is it Feasible?

Giancarlo Marra, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Determining the Benefit of Therapy for Biochemically Recurrent Prostate Cancer:

David Einstein, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Molecular Imaging at Prostate Cancer Biochemical Recurrence

Hong Song, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

SESSION III: POPULATION OF MEN WITH ADVANCED PROSTATE CANCER

Guidelines for Management of Advanced PC: NCCN and Beyond

Marc B. Garnick, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Sequencing of Treatment

Arnulf Stenzl, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Novel Targeted Treatment and Integration with Precision Diagnostics

Daniel P. Petrylak, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Immunotherapy in Prostate Cancer

Sandy Srinivas, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Fireside Chat: Emerging Advances in Precision Radiation Treatment and Immunotherapy

Steven E. Finkelstein, MD, and Patrick Soon-Shiong, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Radiopharmaceutical Design and Molecular Imaging

Katherine Ferrara, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Radiologic Perspective on Integration of Molecular Imaging and Treatment

Andrei Iagaru, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

PSMA-Targeted Therapy – Clonal Heterogeneity, Neuroendocrine Differentiation, and Finding the Right Sequence of Systemic Treatment

Vikas Prasad, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Medical Oncology Perspective on Integration of Molecular Imaging and Treatment

Diogo Assed Bastos, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

Driving Broader Impact: The Emerging Role of Radio-Ligand Therapies

Ilya Gipp, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 16, 2025.

SESSION IV: PRECISION DIAGNOSTICS AND EMERGING ROLE OF IMAGE-TARGETED, MINIMALLY INVASIVE TREATMENT: Multimodality Diagnostics for Improved Target Definition, Patient Selection, Monitoring & Outcomes

Focal Therapy Patient Selection Role of Multiomics

John Feller, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Quantitative MRI Reading: Applications in Prostate Cancer

Victoria Bird, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Energy Sources and Emerging Clinical Indications

Jurgen Futterer, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Focal Therapy Patient Selection: Urologist Perspective

Geoffrey Sonn, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Micro-Ultrasound and Irreversible Electroporation (IRE) for Treatment of Prostate Cancer

Xiaosong Meng, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Focal Treatment Recurrences and Management

Abhinav Sidana, MD, MPH, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Review and Update – Imaging for Improving Post-Ablation Assessment and Developing Short-Term Patient Outcomes

Faina Shtern, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Standardized MRI and Molecular Imaging Reporting for Treatment Follow-up

Daniel Margolis, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Overview of the Current Approaches to Standardized MRI Reporting

Francesco Giganti, MD, PhD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

MRI After FT: Toronto Experience

Sangeet Ghai, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

The Use of PSMA PET/CT Scan in Patients with Prostate Cancer Treated with Focal Therapy

Giovanni Lughezzani, MD, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

Evaluating [68Ga]-Ga PSMA PET/CT for Detecting Prostate Cancer Recurrence Post-High-Intensity Focused Ultrasound and Brachytherapy: A Single-Center Retrospective Study

Andrea Di Giorgio, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

KEYNOTE PRESENTATIONS

Precision Care and Health Disparities in Prostate Cancer – Risk Assessment in Black Men

Adam B Murphy, MD, MBA, MSCI, presented this lecture during the 9th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 17, 2025.

PRESENTATION OF WINNING ABSTRACTS

First Place:
Targeted Prostate Health Checks to Address Healthcare Inequalities in Prostate Cancer Diagnoses – Results of a Feasibility Pilot for High-Risk Populations in Northeast London
Prabhakar Rajan, MD, Consultant
Urologist, Professor of Urology and Robotic Surgery, and Chair of Urology, Queen Mary University of London, United Kingdom

Second Place:
Seminal Plasma Proteomics for Prostate Cancer Detection and Risk Stratification – A Multicenter Study
Fernanda Orellana, MD
Urologist Universidade Federal de São Paulo (UNIFESP)

Third Place:
Evaluation of Urinary Prostate Cancer Biomarkers in Predicting Biopsy Outcome
Paula Robins, PA, Patient Care Navigator, University of California, San Diego

Fourth Place:
Financial Toxicity and Distress Among Prostate Cancer Patients in a Single Center in Lebanon – A Cross-Sectional Study
Anthony Mina, MD, MPH
Urology Resident
Holy Spirit University, Kaslik, Lebanon