Daniel Margolis, MD, Author at Grand Rounds in Urology

Daniel Margolis, MD

Weill Cornell Medical College

New York, New York

Daniel Margolis, MD, is a Professor of Radiology at Weill Cornell Medical College in New York, New York. Dr. Margolis also serves as Chair of the Cancer Institutional Review Board for Weill Cornell Medicine. He specializes in abdominal imaging and is experienced in prostate magnetic resonance imaging, tumor imaging, and vascular ultrasonography.

Dr. Margolis earned his medical degree from the University of Southern California in Los Angeles. He then completed an internship in Internal Medicine and a residency in Radiology-Diagnostics at the University of California, Los Angeles. Dr. Margolis subsequently completed a fellowship in Advanced Imaging at Stanford University in Stanford, California. Dr. Margolis also completed the K30 Graduate Training Program in Translational Investigation at the University of California, Los Angeles.

Dr. Margolis is a member of the American College of Radiology Prostate Imaging Reporting and Data Systems steering committee, and has been an invited lecturer for the Society of Abdominal Radiology, International Society for Magnetic Resonance in Medicine, and Radiological Society of North America, as well as lectures abroad. He has over 320 publications regarding using MRI for detecting and characterizing prostate cancer.

Talks by Daniel Margolis, MD

Standardized MRI and Molecular Imaging Reporting for Focal Therapy Follow-up

Daniel Margolis, MD | Mar 2026

Daniel Margolis, MD, explains standardized reporting for follow-up after focal therapy and how structured criteria can guide decisions on imaging and biopsy.

Standardized MRI and Molecular Imaging Reporting for Focal Therapy Follow-up – Creating Imaging Based Short and Intermediate Outcomes

Daniel Margolis, MD | Jun 2024

Daniel Margolis, MD, focuses on standardized MRI and molecular imaging reporting for follow-up in prostate cancer focal therapy. Implementing standardized protocols for imaging evaluation post-focal therapy aims to ensure consistency and reliability across different healthcare settings, facilitate accurate comparison of treatment outcomes, and enable evidence-based decision-making.
Multiparametric MRI (mpMRI) is a cornerstone of the follow-up strategy. By utilizing standardized reporting systems such as the Prostate Imaging Reporting and Data System (PI-RADS), radiologists can systematically assess post-treatment changes, detect residual or recurrent disease, and monitor treatment response. Dr. Margolis also discusses molecular imaging techniques that offer additional insights into treatment response and disease activity at a molecular level. Novel tracers and imaging agents target specific biological markers associated with prostate cancer, enhancing the precision and sensitivity of post-treatment assessments.
Dr. Margolis emphasizes the importance of integrating these imaging modalities into a cohesive framework. This approach not only aids in the early detection of treatment failure or disease recurrence but also guides timely intervention and adjustment of therapeutic strategies.

Image-Guided Biopsy and Treatment

Daniel Margolis, MD | Jan 2020

Daniel Margolis, MD, discusses the evolving role of imaging in biopsy and focal therapy guidance. He reviews the advantages of current image-targeting techniques, including MRI/ultrasound fusion and MRI in-bore targeting.