Recurrent Prostate Cancer: Enzalutamide Monotherapy and Alternatives
Dr. Javier-DesLoges reviews risk assessment, evaluation, salvage strategies, and the role of enzalutamide in biochemical recurrence of prostate cancer.
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Juan Javier-DesLoges, MD, MS, FACS, is an Assistant Professor of Urology and a Urologic Oncologist at the University of California, San Diego. Dr. Javier-DesLoges specializes in robot-assisted minimally invasive surgery as well as transperineal procedures, including SpaceOAR Hydrogel (a rectal spacer), prostate biopsy, and cryoablation. His clinical focus is on the management of prostate, bladder, kidney, and ureteral cancer.
Dr. Javier-DesLoges earned his medical degree from Rutgers New Jersey Medical School in Newark. He completed his residency in Urology at Yale University in New Haven, Connecticut, and then completed his fellowship in Urology at Rutgers New Jersey Medical School in Newark.
Dr. Javier-DesLoges’ research has been published in several books and journals, including Cancer, Journal of Urology, Urology, Journal of the American Medical Association (JAMA), and Urologic Oncology. He currently serves on the editorial board for the Journal of Urology. He is a co-investigator on clinical trials and holds a certificate in clinical trial design and development. His research grants have been funded by the National Institutes of Health and Congressionally Directed Medical Research Programs. Dr. Javier-DesLoges has served on numerous national committees, including the American Medical Association, American Urological Association, and the Urology Care Foundation.
Juan Javier-DesLoges, MD, MS, FACS | Mar 2026
Dr. Javier-DesLoges reviews risk assessment, evaluation, salvage strategies, and the role of enzalutamide in biochemical recurrence of prostate cancer.
Read MoreJuan Javier-DesLoges, MD, MS, FACS | Mar 2026
Dr. Javier-DesLoges argues for focal therapy to reduce morbidity in selected men with localized prostate cancer, emphasizing imaging-based selection and close surveillance.
Read MoreJuan Javier-DesLoges, MD, MS, FACS | Feb 2025
Juan Javier-DesLoges, MD, MS, focuses on contemporary advancements in prostate cancer detection, emphasizing the integration of biomarkers and MRI for biopsy decision-making. In this 5-minute presentation, he references recent guidelines, which advocate biomarkers and MRI as tools for determining the necessity of biopsies. Studies comparing biomarkers such as 4K, PHI, SelectMDx, and XODX illustrate their ability to enhance the specificity and accuracy of cancer detection compared to PSA alone.
Dr. Javier-DesLoges stresses that MRI further refines risk stratification when combined with biomarkers. He underscores the complementary role of these tools, advocating their combined use to optimize diagnostic outcomes for patients with intermediate PSA levels.
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