Leonard G. Gomella, MD, FACS presented “Genetic Testing for Inherited Prostate Cancer” during the 19th Annual Future Directions in Urology Symposium on August 11, 2018 in Colorado Springs, Colorado.
How to cite: Gomella, Leonard G. “Genetic Testing for Inherited Prostate Cancer” August 11, 2018. Accessed [date today]. https://grandroundsinurology.com/genetic-testing-for-inherited-prostate-cancer/
Genetic Testing for Inherited Prostate Cancer – Summary
Leonard G. Gomella, MD, FACS, discusses the evolving role of genetic testing for inherited family risks in prostate cancer patients. He advises urologists to be attentive to recent developments in genetic testing in order to better detect cancers in individual patients and their family members.
Inherited Family Risks
In general, urologists have always inquired into a patient’s family medical history when treating prostate cancer patients. However, urologists now recognize that patients can have inherited risks beyond prostate cancer, such as breast, ovarian, or pancreatic cancer, or melanoma. Recent data supports that BRCA1 and BRCA2, the established target genes in the setting of breast and ovarian cancer, also operate in prostate cancer. Therefore, urologists must perform more comprehensive family histories than in the past.
Advice to Urologists Regarding Available Genetic Tests
There are a variety of general and prostate-cancer-specific genetic testing panels available to assess patients has a suspected inherited familial cancer syndrome risk. Dr. Gomella advises urologists to increase their awareness of patients’ family history. Attentiveness to inherited family risks not only helps to detect prostate cancer in an individual patient. It also helps to detect other cancers in the patient and the patient’s family members. Additionally, urologists should partner with a professional medical genetic counselor.
About Dr. Gomella
Dr. Gomella is the Chairman of the Department of Urology at Jefferson University Hospitals. Due to his involvement in developing new diagnostic techniques for prostate cancer through Jefferson’s Kimmel Cancer Center, he has much experience in genetic testing for inherited prostate cancer.
About the Future Directions in Urology Symposium
The Future Directions in Urology Symposium (FDUS) is an annual collaborative meeting with a faculty consisting of the top researchers, physicians, and educators in the field of urology. During FDUS, experts provide updates on recent developments and debate innovative management approaches in genitourinary cancers and urologic conditions. Subsequently, the experts devise consensus statements in accordance with the discussions held in the meeting.
In this video, Dr. Gomella discloses the thesis of the discussion he led during FDUS.