Germline and Somatic Markers
Dr. Leonard Gomella outlines the evolution of germline and somatic testing and their impact on targeted prostate cancer therapy.
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Leonard G. Gomella, MD, FACS, serves as the Bernard W. Godwin, Jr. Professor of Prostate Cancer, Chairman of the Department of Urology, Senior Director of Clinical Affairs for the Sidney Kimmel Comprehensive Cancer Center, and the Enterprise Vice President of Urology at the Jefferson Health System at Thomas Jefferson University in Philadelphia, Pennsylvania. Dr. Gomella's lab, a part of the Jefferson Sidney's Kimmel Comprehensive Cancer Center, is involved in clinical research for the development of techniques to treat cancers.
Dr. Gomella earned his medical degree and completed residencies in General Surgery and Urology at the University of Kentucky in Lexington, Kentucky. He then completed a fellowship in Urologic Oncology, in the Department of Surgery, at the National Cancer Institute in Bethesda, Maryland.
Dr. Gomella's team was first to use RT-PCR to detect micrometastasis in patients with prostate cancer, a discovery that led to a new field of investigation in this disease. He is also recognized as an early contributor to urologic laparoscopy, initiating the program at Jefferson in 1990. Dr. Gomella has given almost 500 presentations at local, national and international meetings and has authored over 300 papers, chapters, and monographs in the field of Urology. He has also authored and edited 54 editions of 17 different books for medical students, residents, and practicing physicians, many of which have been translated into foreign languages. Dr. Gomella is the editor-in-chief of the 5 Minute Urology Consult, and laparoscopy section editor for Glenn’s Urologic Surgery. Dr. Gomella is known for the Clinician's Pocket Reference, now in its 11th edition, a widely used reference for medical students and health care providers.
Leonard G. Gomella, MD, FACS | Mar 2026
Dr. Leonard Gomella outlines the evolution of germline and somatic testing and their impact on targeted prostate cancer therapy.
Read MoreLeonard G. Gomella, MD, FACS | Aug 2025
Leonard G. Gomella, MD, FACS, explores the role of germline and somatic testing in guiding prostate cancer management decisions.
Read MoreLeonard G. Gomella, MD, FACS, and Brian T. Helfand, MD, PhD, discuss genetic testing in prostate cancer risk assessment and management.
Read MoreLeonard G. Gomella, MD, FACS | May 2025
Leonard G. Gomella, MD, FACS, explores bladder cancer treatment, particularly in the context of intermediate-risk, BCG-naïve disease.
Read MoreLeonard G. Gomella, MD, FACS | Jan 2025
Leonard G. Gomella, MD, FACS, presents a comprehensive overview of combining secondary biomarkers with MRI.
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