Martin Gleave, MD, FRCSC, FACS, presented “More Arrows in Our Quiver – Targeting the Adaptive Molecular Landscape of Advanced Prostate Cancer” for the Grand Rounds in Urology audience in September, 2019.

How to cite: Gleave, Martin. “More Arrows in Our Quiver – Targeting the Adaptive Molecular Landscape of Advanced Prostate Cancer” September, 2019. Accessed May 2024. https://grandroundsinurology.com/more-arrows-in-our-quiver-targeting-the-adaptive-molecular-landscape-of-advanced-prostate-cancer/

More Arrows in Our Quiver – Targeting the Adaptive Molecular Landscape of Advanced Prostate Cancer – Summary:

Martin Gleave, MD, FRCSC, FACS, Co-Founder and Director of the Vancouver Prostate Centre, reviews the molecular mechanisms of treatment resistance in metastatic castrate-resistant prostate cancer, as well as efforts to refine precision treatment of disease. He discusses how defining these mechanisms has yielded new processes and drugs, shows how molecular subclassification is key to drug selection and sequencing, and highlights new studies demonstrating how circulating tumor DNA monitoring can show real-time genetic adaptations in cancer cells.