Sigrid V. Carlsson, MD, PhD, MPH, presented “Keynote Lecture: Has Prostate Cancer Mortality Increased?” during the 27th Annual Southwest Prostate Cancer Symposium conference on October 17, 2024, in Scottsdale, Arizona.
How to cite: Carlsson, Sigrid V. “Keynote Lecture: Has Prostate Cancer Mortality Increased?.” October 17, 2024. Accessed Feb 2025. https://grandroundsinurology.com/keynote-lecture-has-prostate-cancer-mortality-increased/
Keynote Lecture: Has Prostate Cancer Mortality Increased? – Summary
Sigrid V. Carlsson, MD, PhD, MPH, delivers an 8-minute presentation exploring the nuanced trends in prostate cancer mortality worldwide. She highlights that prostate cancer mortality in the US has recently stagnated or increased. This change correlates with reduced PSA screening, influenced by the US Preventive Services Task Force guidelines, in 2012. Globally, the incidence and mortality of prostate cancer vary, with Northern and Western Europe, North America, and the Caribbean exhibiting the highest rates. In Eastern Europe and parts of Asia and Africa, mortality continues to rise.
Projections indicate that by 2040, the global incidence of prostate cancer will double, with deaths increasing by 85%. Regions with lower healthcare access face disproportionately high late-stage diagnoses and mortality rates. Dr. Carlsson emphasizes reversing negative trends through tailored guidelines and equitable healthcare access. Her analysis provides a critical perspective on addressing the disparities in prostate cancer outcomes and the need for strategic advancements in screening and treatment globally.
About the 27th Annual Southwest Prostate Cancer Symposium:
Presented by Program Chairs Nelson N. Stone, MD, Richard G. Stock, MD, and William K. Oh, MD, this conference educated attendees about advances in the management of localized and advanced prostate cancer, with a focus on imaging, technology, and training in the related devices. It included a scientific session, as well as live demonstrations of surgical techniques. You can learn more about the conference here.
ABOUT THE AUTHOR
Sigrid V. Carlsson, MD, PhD, MPH, is Director of Clinical Research at Memorial Sloan Kettering Cancer Center’s (MSKCC) Josie Robertson Surgery Center and Assistant Attending Epidemiologist, with dual appointments in MSKCC’s Departments of Surgery (Urology Service) and Epidemiology and Biostatistics. Her line of research focuses on screening and early detection of prostate cancer, including multiplex testing and risk-stratified strategies that incorporate clinical information, biomarkers and magnetic resonance imaging, as recently funded by an NIH/NCI U01 award (PI: Carlsson).
Dr. Carlsson also serves as Associate Professor of Experimental Urology affiliated with the Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, in Sweden, where she is an investigator of two large randomized controlled trials of prostate cancer screening (GOTEBORG-1&2), as recently published in the New England Journal of Medicine (Hugosson J, et al. N Engl J Med 2022). In addition, Dr. Carlsson is Adjunct Senior Lecturer in the Department of Translational Medicine in the Division of Urological Cancers in the Medical Faculty at Lund University, Lund, Sweden.
Dr. Carlsson recently completed a K22 career development award from the NIH/NCI to improve shared decision-making for breast and prostate cancer screening. She serves on the National Comprehensive Cancer Network (NCCN) and is a panel member for the American Urological Association (AUA) guidelines for early detection of prostate cancer. Before pursuing postdoctoral studies in urologic oncology at MSKCC, Dr. Carlsson was a physician in Sweden. She earned her MD and PhD from Gothenburg University in Sweden and earned an MPH from Harvard TH Chan School of Public Health in Boston, Massachusetts.
