Thomas M. Wheeler, MD, presented “​Prostate: Anatomic Considerations” during the 7th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 21, 2023.

How to cite: Wheeler, Thomas M. Prostate: Anatomic Considerations.” September 21, 2023. Accessed May 2024. https://grandroundsinurology.com/prostate-anatomic-considerations/

Prostate: Anatomic Considerations – Summary

Thomas M. Wheeler, MD, presents anatomic considerations relating to the prostate and prostate cancer for clinicians. He begins by illustrating why prostate cancer rarely metastasizes via the neighboring rectum, usually spreading to the rest of the body via the neurovascular bundle.

Dr. Wheeler then presents a few examples of prostate cancer, noting that most prostate cancer is multifocal. He presents multiple cross-sections of prostate cancer to illustrate the differences between multifocal cancer, index cancer, and large volume unifocal prostate cancer.

Dr. Wheeler concludes by reviewing the history of differentiating prostate zones, tumor volume and Gleason scores in prostate cancer, and what they indicate in patient prognosis. He notes that levels of capsular invasion, perineural invasion diameter, and presence of intraductal carcinoma are all significant prognostic indicators.

 

The Global Summit on Precision Diagnosis and Treatment of Prostate Cancer is a unique multi-disciplinary forum organized to inform the key health care stakeholders about the emerging advances in clinical case and research and create a consensus-based vision for the future of precision care and educational and research strategy for its realization. The mission of the Summit is to fill the currently existing gap between the key experts of in vivo imaging, the world authorities in the in vitro fluid- and tissue-based molecular diagnostics, including genomics, and thought leaders in the development of novel observation strategies (e.g., active surveillance, or AS) and therapeutic interventions.