James S. Wysock, MD, MSc presented “The Application of Stimulated Raman Histology to Urologic Malignancies – Human and Artificial Intelligent Assessment” during the 2023 Frontiers in Oncologic Prostate Care and Ablative Local Therapy symposium on November 10, 2023, in Chicago, Illinois.

How to cite:  Wyscock, James S. “The Application of Stimulated Raman Histology to Urologic Malignancies – Human and Artificial Intelligent Assessment” November, 2023. Accessed Nov 2025. https://grandroundsinurology.com/the-application-of-stimulated-raman-histology-to-urologic-malignancies-human-and-artificial-intelligent-assessment/

The Application of Stimulated Raman Histology to Urologic Malignancies – Human and Artificial Intelligent Assessment Summary

James S. Wysock, MD, MSc, explores Stimulated Raman Histology (SRH) in diagnosing and managing urologic malignancies, emphasizing the role of both human and artificial intelligence (AI) assessments. SRH, a cutting-edge imaging technique, provides rapid, label-free histological images of tissues, enabling real-time intraoperative diagnosis. Dr. Wysock highlights SRH’s high specificity and sensitivity in identifying cancerous tissues, potentially reducing reliance on frozen sections and improving surgical outcomes.

Dr. Wysock discusses integrating AI into SRH image analysis, including creating training datasets, validation studies, and clinical trials. The potential for AI to enhance diagnostic precision and minimize human error is a key focus. Data show that SRH, combined with AI assessment, significantly improves the accuracy of margin detection during prostate and kidney cancer surgeries.

Frontiers in Oncologic Prostate Care and Ablative Local Therapy (FOCAL) is an outstanding program on prostate imaging, transperineal interventions, and ablative treatments for prostate cancer and benign prostatic hyperplasia. Bringing together community-based, academic, and industry partners, FOCAL offers lectures by world-renowned faculty and hands-on training workshops on in-office transperineal interventions, fusion-guided prostate ablation and state-of-the-art BPH management with novel technologies. 

ABOUT THE AUTHOR

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James S. Wysock, MD, MSc, is a Clinical Assistant Professor of Urology at New York University Grossman School of Medicine in New York, New York. Dr. Wysock also serves as the Division Chief of Urology at Bellevue Hospital Center in New York City. His research focuses on advanced imaging techniques and treatment tools to optimize cancer diagnostics and therapy. Dr. Wysock’s clinical research efforts focus on image-guided prostate cancer diagnosis and treatment, including MRI-US fusion biopsy and partial gland prostate ablation techniques, and his specialization in urologic oncology includes cancers of the kidneys, bladder, ureters, testes, and prostate.