Daniel Y. Song, MD, presented “Emerging Role of Focal Therapy in the Management of Prostate Cancer” during the 8th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on October 8, 2024.
How to cite: Song, Daniel Y. “Emerging Role of Focal Therapy in the Management of Prostate Cancer.” October 8, 2024. Accessed Feb 2025. https://grandroundsinurology.com/emerging-role-of-focal-therapy-in-the-management-of-prostate-cancer/
Emerging Role of Focal Therapy in the Management of Prostate Cancer – Summary
Dr. Daniel Song, MD, Professor of Radiation Oncology and Director of GU Radiotherapy at Johns Hopkins University, presents a detailed 9-minute discussion on focal brachytherapy for prostate cancer. He emphasizes its rationale, centered on targeting the index lesion that significantly impacts clinical outcomes, using advanced tools like multiparametric MRI and PSMA-targeted imaging. He asserts that focal brachytherapy minimizes treatment volume, reducing morbidity and patient anxiety while preserving quality of life.
Dr. Song covers studies from France and TUUS highlighting the benefits of focal brachytherapy, and introduces a phase II trial using palladium-103 brachytherapy and multimodal imaging. An example illustrates how PSMA imaging reveals additional lesions missed by MRI, influencing clinical target volume adjustments.
Dr. Song is optimistic about the role of focal therapy in the future of prostate cancer care, inviting viewers to explore this evolving field.
The Global Summit on Precision Diagnosis and Treatment of Prostate Cancer is a unique multi-disciplinary forum organized to inform the key health care stakeholders about the emerging advances in clinical case and research and create a consensus-based vision for the future of precision care and educational and research strategy for its realization. The mission of the Summit is to fill the currently existing gap between the key experts of in vivo imaging, the world authorities in the in vitro fluid- and tissue-based molecular diagnostics, including genomics, and thought leaders in the development of novel observation strategies (e.g., active surveillance, or AS) and therapeutic interventions.
ABOUT THE AUTHOR
Dr. Daniel (Danny) Song is a Professor of Radiation Oncology, with joint appointments in Urology and Oncology. He serves as the Co-director of the Prostate Cancer Multidisciplinary Clinic at the Johns Hopkins Hospital and the Physician Advisor and Director of Faculty Affairs for the Department of Radiation Oncology and Molecular Radiation Sciences. His area of clinical expertise is in the management of genitourinary cancers, including cancers of the prostate, bladder and urinary tract, and testicular cancer.