Amy E. Krambeck, MD, presented “Holmium Laser Enucleation of the Prostate (HoLEP): Current Era Techniques and Outcomes” during the 44th Annual Ralph E. Hopkins Urology Seminar on February 5, 2025, in Jackson Hole, Wyoming.
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How to cite: Krambeck, Amy E. “Holmium Laser Enucleation of the Prostate (HoLEP): Current Era Techniques and Outcomes.” February 5, 2025. Accessed Mar 2025. https://grandroundsinurology.com/holep-current-era-techniques-and-outcomes/
Holmium Laser Enucleation of the Prostate (HoLEP): Current Era Techniques and Outcomes – Summary
Amy E. Krambeck, MD discusses holmium laser enucleation of the prostate (HoLEP), emphasizing its advantages, indications, and technical refinements. She begins this 21-minute presentation by defining HoLEP as a simple prostatectomy performed entirely endoscopically, with no size limitations on prostate gland removal.
Dr. Krambeck highlights HoLEP’s versatility, outlines a streamlined patient evaluation process, and stresses the importance of prostate cancer screening before surgery. She presents data from a randomized trial comparing different scope sizes and shares her preference for a larger scope. She describes her systematic technique, emphasizing tissue traction, precise dissection, and minimizing bleeding, illustrated by a procedure video.
Dr. Krambeck presents long-term studies demonstrating HoLEP’s superior durability compared to TURP, with significantly lower retreatment rates over 18 years. Advancements in holmium laser technology, particularly pulse modulation, are discussed, with Dr. Krambeck stressing its improved efficiency, reduction in bleeding, and enhanced enucleation speed.
About The 44th Annual Ralph E. Hopkins Urology Seminar:
The Ralph E. Hopkins Urology Seminar is a multi-day meeting focused on training urologists in the latest in assessing, diagnosing, and treating urologic conditions in the clinical setting. Updates are provided on urologic cancers, stone disease, urologic reconstruction, female urology, infertility, sexual function, emerging surgical techniques, and general urology. The 44th iteration of the meeting took place from February 5th to February 8th, 2025, in Jackson Hole, Wyoming.
For further educational activities from this conference, visit our collection page.
ABOUT THE AUTHOR
Amy E. Krambeck, MD, is a professor of urology at Northwestern University Feinberg School of Medicine in Chicago, Illinois. Dr. Krambeck earned her medical degree from the University of Missouri School of Medicine in Columbia. She completed her urology residency at the Mayo Clinic in Rochester, Minnesota, where she received extensive training and refined her surgical expertise. Following her residency, Dr. Krambeck pursued an endourology fellowship at the Methodist Institute for Kidney Stone Research in Indianapolis, Indiana.
Dr. Krameck specializes in the surgical and medical management of stone disease and benign prostatic hyperplasia (BPH), and she has alleviated the symptoms of many patients. Her research focuses on the pathogenesis of stone disease and novel treatments for urolithiasis during pregnancy.
Dr. Krambeck began her career as an endourologist at the Mayo Clinic's Department of Urology, where she demonstrated exceptional surgical skills and a strong commitment to patient care. In 2016, Dr. Krambeck joined Indiana University, where she led the benign urologic diseases division until 2020. Her leadership and expertise significantly advanced the division, offering patients innovative treatments for various urologic conditions.
Dr. Krambeck's dedication to her patients, extensive knowledge, and research contributions have established her as a leading figure in urology. She continues to influence the future of urologic care through her clinical excellence and academic endeavors.
