Phillip J. Koo, MD, reviews the data evaluating the use of radium-223 in combination with AR inhibitors for treating patients with CRPC. He discusses findings from the ERA 223 trial and the issues with this combination it highlighted, especially regarding bone health.
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John C. Chang, MD, PhD, examines the potential of MRI for staging bladder cancer, emphasizing MRI’s facility in differentiating between muscle invasive and non-muscle invasive bladder cancer (NMIBC). He also acknowledges that MRI scanning can lead to overstaging, and that CT can be effective for detecting higher stages of bladder cancer.
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John C. Chang, MD, PhD, compares advantages and disadvantages of MRI-guided biopsy and transrectal ultrasound-guided (TRUS) biopsy. He emphasizes MRI-guided biopsy’s detection rates and its effectiveness in patients undergoing repeat biopsies, while acknowledging its relative inefficiency and limitations in low grade cancers.
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Phillip J. Koo, MD, discusses conventional prostate cancer imaging techniques and the need for advanced imaging techniques in order to better detect recurrent disease. He then argues that fluciclovine (18F) positron emission tomography/computed tomography (PET/CT) could satisfy this unmet need.
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Phillip J. Koo, MD, provides a brief update of recent approvals and ongoing trials in in imaging, therapeutic, and theranostic radiopharmaceutical agents, such fluciclovine, radium-223, and lutetium-177.
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