Harvard Medical Center

Christopher J. Sweeney, MBBS, gives an overview of the ENZAMET study, a companion to the ARCHES trial, the latter of which demonstrated a survival benefit in all versions of mHSPC (metastatic hormone-sensitive prostate cancer) with the use of enzalutamide. Dr. Sweeney discusses how ENZAMET builds on the research conducted with ARCHES, the differences between enzalutamide and chemotherapy for high-burden, rapidly progressing disease, and why monotherapy should be phased out for PCa treatment in most patients.