Richard G. Stock, MD, compares long-term overall survival and morbidity outcomes of brachytherapy alone versus a brachytherapy/ external beam combination in intermediate and high risk prostate cancer. He also discusses factors that could affect those outcomes, such as the patient’s intermediate-risk features, duration of androgen deprivation therapy (ADT), and technique of seed implantation.
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Richard G. Stock, MD, discusses rectal toxicity related to prostate brachytherapy seed spacing and dosage. He then describes methods to reduce rectal toxicity, like combining brachytherapy with androgen deprivation therapy (ADT) and using balloon or hydrogel spacers.
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Nelson N. Stone, MD, discusses changes in urinary symptoms and erectile function, as measured by the International Prostate Symptom Score (IPPS), at 10 and 15 years following prostate brachytherapy. Subsequently, he advises clinicians on best practices in seed implantation and long-term management to optimize cancer control and minimize adverse symptoms.
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Richard G. Stock, MD, discusses advanced imaging for local, nodal, and distant recurrent prostate cancer, emphasizing positron emission tomography (PET) imaging. He specifically describes the mechanisms of action and advantages of the 18F-FACBC (fluciclovine) radiotracer for PET imaging.
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Nelson N. Stone, MD, argues that MRI’s limitations make it insufficient for evaluating and managing prostate cancer patients under consideration for active surveillance (AS) or targeted focal therapy (TFT). Instead, urologists should consider technology like the under-development 3DBiopsy™ system, with a transperineal needle along with mapping software. This approach can detect the precise location of lesions and create a roadmap for treatment planning.
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