Johns Hopkins University School of Medicine Archives

Transperineal vs Transrectal Biopsy Clinical Trials: Mo’ Data Mo’ Problems

Posted by Arvin George, MD | Dec 2024

Arvin K. George, MD, delves into the nuances of prostate cancer biopsy techniques, focusing on the comparison between transperineal and transrectal approaches.

In this 14-minute presentation, Dr. George shares that transperineal and transrectal biopsies demonstrate equivalent cancer detection rates, particularly for clinically significant prostate cancer. However, some retrospective data suggest potential advantages of transperineal biopsy in specific anatomical areas, with notable studies emphasizing the reduced risk of infections with transperineal biopsy. Dr. George also discusses a decreased need for antibiotics and the use of local anesthesia in a transperineal approach.

Further, Dr. George reflects on the implications for clinical practice, antibiotic stewardship, and cost-effectiveness for transperineal and transrectal approaches. His talk provides a comprehensive synthesis of current evidence, encouraging a balanced and thoughtful approach to biopsy method selection.

Emerging Role of Focal Therapy in the Management of Prostate Cancer

Posted by Daniel Y. Song, MD | Dec 2024

Daniel Y. Song, MD, discusses focal brachytherapy for treating prostate cancer.

Renal Ablation Technologies – Impact on the Treatment of Small Renal Masses

Posted by Thomas W. Jarrett, MD | Oct 2024

Thomas W. Jarrett, MD, explores the evolving role of renal ablation technologies in managing small renal masses (SRMs), highlighting their increasing importance as an alternative to traditional surgical approaches. In this 20-minute talk, he provides a detailed overview of the various ablation techniques, including radiofrequency ablation (RFA), cryoablation, and microwave ablation, emphasizing their distinct mechanisms of action and clinical applications.

The presentation delves into the outcomes associated with renal ablation, discussing the advantages and disadvantages of the different ablation options. Dr. Jarrett also addresses the limitations and challenges of renal ablation, including the potential for incomplete tumor destruction and the difficulties in monitoring long-term outcomes.

The Battle of Biopsies: Results of a Multi-institutional Randomized Trial of Transrectal vs Transperitoneal Prostate Biopsy

Posted by Mohamad E. Allaf, MD | Sep 2024

In this 21-minute conversation, Mohammed E. Allaf, MD, Johns Hopkins University, Baltimore, Maryland, advocates for a reevaluation of current biopsy practices, suggesting that the transperitoneal approach may offer a safer option for patients, particularly in the context of rising concerns over antibiotic resistance.

iTIND: How I Do It

Posted by Amin S. Herati, MD | Aug 2024

Amin S. Herati, MD, provides an in-depth analysis of the implantation of the Temporary Implantable Nitinol Device (iTIND) for the treatment of benign prostatic hyperplasia (BPH). His discussion emphasizes the procedural details, benefits, and practical considerations of using iTIND, a minimally invasive therapy designed to relieve urinary symptoms associated with BPH.

Dr. Herati describes the indications for iTIND, highlighting its suitability for patients with moderate to severe BPH who are seeking alternatives to medication or more invasive surgical procedures. The procedural technique is meticulously detailed; Dr. Herati emphasizes the technical aspects critical to the procedure’s success, such as the precise placement of the device and careful monitoring during the implantation and removal processes.

The benefits of iTIND are highlighted, including its minimally invasive nature, rapid symptom relief, and preservation of sexual function. Additionally, the low incidence of complications, such as temporary dysuria and hematuria, is discussed. Challenges and limitations of iTIND are also addressed.