Baris Turkbey, MD, presented “AI and Prostate Imaging and Biopsy” during the 2024 Frontiers in Oncologic Prostate Care and Ablative Local Therapy symposium on October 17, 2024, in San Diego, California.
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How to cite: Turkbey, Baris. “AI and Prostate Imaging and Biopsy.” October, 2024. Accessed Jan 2025. https://grandroundsinurology.com/ai-and-prostate-imaging-and-biopsy/
AI and Prostate Imaging and Biopsy – Summary
Baris Turkbey, MD, discusses the transformative potential and challenges of artificial intelligence (AI) in prostate imaging and biopsies. He begins this 19-minute presentation detailing the benefits of MRI-guided prostate biopsies for localized cancer diagnosis. However, he highlights significant limitations, including low interobserver agreement among radiologists, undermining MRI’s reliability in broader clinical applications.
Turkbey explains how AI can address challenges by standardizing imaging quality and assisting in lesion detection. He references a large-scale European study (PI-CAI) demonstrating AI’s ability to detect clinically significant cancers. Importantly, he illustrates the critical yet underexplored interaction between AI and radiologists, showing that while AI often detects lesions missed by radiologists, its findings are sometimes disregarded, resulting in missed cancers.
Dr. Turkbey introduces an AI model developed at NCI that demonstrates high performance in lesion detection with low false positives. This model, employed for prospective biopsies, radiation oncology planning, and focal therapy, automates prostate segmentation and lesion identification processes, delivering results within minutes. However, his research reveals that human radiologists outperform AI in estimating tumor burden, particularly for PIRADS 4 lesions.
Frontiers in Oncologic Prostate Care and Ablative Local Therapy (FOCAL) is an outstanding program on prostate imaging, transperineal interventions, and ablative treatments for prostate cancer and benign prostatic hyperplasia. Bringing together community-based, academic, and industry partners, FOCAL offers lectures by world-renowned faculty and hands-on training workshops on in-office transperineal interventions, fusion-guided prostate ablation and state-of-the-art BPH management with novel technologies.
ABOUT THE AUTHOR
Dr. Turkbey obtained his medical degree from Hacettepe University in Ankara, Turkey in 2003. He completed his residency in Diagnostic and Interventional Radiology at Hacettepe University. He joined Molecular Imaging Branch (MIB), National Cancer Institute, NIH in 2007. His main research areas are imaging of prostate cancer (multiparametric MRI, PET CT), image guided biopsy and treatment techniques (focal therapy, surgery and radiation therapy) for prostate cancer and artificial intelligence. Dr. Turkbey is a member of Prostate Imaging Reporting & Data System (PI-RADS) Steering Committee. He is the Head of the Magnetic Resonance Imaging section in MIB and the Artificial Intelligence Resource (external link) in MIB.
