David Utz

David Utz

Disclosures:

Talks by David Utz

TMPRSS2, ACE 2, and the Potential Role of 5ARIs and GNRH Analogues in Inhibiting COVID-19 Infection

TMPRSS2, ACE 2, and the Potential Role of 5ARIs and GNRH Analogues in Inhibiting COVID-19 Infection

Posted by | May 2020

L. Michael Glodé, MD, FACP, Professor Emeritus at the University of Colorado Cancer Center and a medical oncologist at the Shaw Regional Cancer Center in Edwards, Colorado, discusses the mechanism of action of the TMPRSS2 and ACE2 pathways, and their relationship to the host-cell entry of COVID-19. He goes on to discuss a clinical trial using the serine protease inhibitor Camostat, noting how 5ARIs and GNRH analogues could act as a target for prevention and possible treatment of COVID-19. He also discusses the results of an Italian observational study which demonstrated how prostate cancer patients receiving ADT appear to be partially protected from COVID-19 infection.

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New Paradigm for the Treatment of Peyronie’s Disease

New Paradigm for the Treatment of Peyronie’s Disease

Posted by | May 2020

Culley C. Carson III, MD, Professor Emeritus at the University of North Carolina School of Medicine, reviews the history of treatment options for Peyronie’s Disease. He then compares clinical results of oral therapies, injection techniques, shock wave therapy, and penile prosthesis. Since first being developed, the efficacy of several of these protocols has improved and patients have experienced a reduction in curvature. Patients with Peyronie’s Disease often report significant negative emotional toll as a result of the condition, and new advances in treatment, such as the combination of drug and lengthening device that improves penile angulation can also improve depression and emotional problems.

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