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Phillip J. Koo, MD

Phillip J. Koo, MD

Banner MD Anderson Cancer Center

Phoenix, Arizona

Phillip J. Koo, MD, is the Chief of Diagnostic Imaging at the Banner MD Anderson Cancer Center in Phoenix, Arizona. Prior to this, he was Chief of Nuclear Medicine and Associate Professor of Radiology at the University of Colorado School of Medicine in Aurora, Colorado. Dr. Koo completed his transitional internship at the University of Pennsylvania Medical Center-Presbyterian and his radiology residency at Pennsylvania Hospital of the University of Pennsylvania Health System in Philadelphia, Pennsylvania. He completed his fellowship at the Harvard Medical School Joint Program in Nuclear Medicine in Boston, Massachusetts. Dr. Koo is a diplomate of both the American Board of Radiology (ABR) and American Board of Nuclear Medicine(ABNM). His academic interests have focused on PET imaging in prostate cancer, response to novel therapies using PET, and data-driven motion correction. He has lectured nationally and internationally on topics related to imaging and radiopharmaceutical based therapies in prostate cancer. In 2022, Dr. Koo was the recipient of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) Presidential Distinguished Service Award.

Disclosures:

Dr. Koo has the following disclosures:
Speaker: Bayer
Consultant: Janssen

Talks by Phillip J. Koo, MD

Challenging Case Discussion Panel

Philip J. Koo, MD, discusses the intricate aspects of prostate cancer diagnosis and treatment. Dr. Koo delves into various challenging cases, shedding light on the significance of personalized approaches tailored to individual patients. The presentation focuses on the utilization of PSMA PET, an advanced imaging technique, which showcases promising performance in detecting localized disease. Drawing from the study conducted by Jeremie Calais, the audience learns about the notable comparison between fluciclovine and PSMA, revealing higher detection rates with the latter.

Furthermore, the potential application of PSMA PET in guiding biopsies is explored, demonstrating its potential to enhance diagnostic accuracy. As the presentation progresses, Dr. Koo provides a compelling case study involving a high-risk prostate cancer patient who presents with back pain and neck swelling. Dr. Koo emphasizes the critical role of biopsy in ensuring tissue concordance, thereby enabling accurate treatment decisions. Throughout the presentation, the complexities of low PSA levels become apparent, underlining the need for comprehensive evaluation in prostate cancer cases.

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Point-Counterpoint: Will Conventional Imaging Become Obsolete? – Pro

Philip J. Koo, MD, delves into the ProPSMA Study, shedding light on the remarkable superiority of PSMA PET over conventional imaging in detecting prostate cancer. The study’s findings showcased an impressive treatment impact of 92% for PSMA PET, surpassing the 65% achieved by conventional imaging, while also demonstrating fewer uncertain results.

Dr. Koo emphasizes that PSMA PET is recommended for patients classified as unfavorable, intermediate, high, and very high-risk, while low or intermediate-risk patients do not require conventional imaging. Moreover, the recognition of PSMA PET’s performance in response assessment is steadily growing, signaling its potential as a reliable and accurate tool in evaluating treatment effectiveness.

The increasing utilization of PSMA PET in other countries hints at an imminent shift in the global landscape of prostate cancer imaging. With ongoing advancements and cost reductions, the wider accessibility and affordability of PSMA PET hold the promise of revolutionizing the field and improving patient outcomes on a global scale.

This lecture is part of a Point-Counterpoint debate. Its opposing lecture is “Point-Counterpoint: Will Conventional Imaging Become Obsolete? – Con.”

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Clinical Update on PSMA Diagnostics and Therapies

Philip J. Koo, MD, discusses the current status of PSMA PET and its role in the diagnosis, treatment, and management of prostate cancer. Dr. Koo highlights the uses of PSMA PET in patients with initial diagnosis, biochemical recurrence, and oligometastatic disease, and the variety of radiopharmaceuticals available for theranostic treatment of patients.

Dr. Koo emphasizes the evolving landscape of prostate cancer staging, with PSMA PET only being appropriate to use at certain stages. Dr. Koo concludes that PSMA PET, while not yet ready for “Prime Time,” is a powerful tool in prostate cancer management, poised to shape the future of diagnosis and patient care.

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