Testosterone Treatment and Prostate Cancer Risk
Thomas J. Walsh, MD, MBA, MS, explores the relationship between testosterone treatment and risk for developing prostate cancer. Dr. Walsh begins by stating that he does not believe that testosterone treatment should be considered a risk factor for prostate cancer. He explains that according to the American Urological Association (AUA), testosterone therapy is appropriate treatment for patients with clinically significant testosterone deficiency after full discussion of potential adverse effects.
Dr. Walsh then outlines the positive and negative effects of testosterone therapy and shares data from a meta-analysis of the effect of testosterone replacement therapy on prostate cancer. He notes the issue of screening bias and compares the longitudinal comorbidities that showed virtually no difference in risk regardless of testosterone treatment.
Dr. Walsh concludes by sharing longitudinal data on cumulative testosterone treatment results that showed no increased risk of prostate cancer. Similarly, data did not show a statistical difference in prostate cancer risk according to the type of testosterone therapy a man received.
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