Morcellation and Potential HoLEP Complications
Amy E. Krambeck, MD, discusses HoLEP morcellation and its associated complications, emphasizing procedural refinements and patient safety.
Read More
Chicago
Holmium Laser Enucleation of the Prostate (HoLEP): Current Era Techniques and Outcomes
Amy E. Krambeck, MD, discusses holmium laser enucleation of the prostate, emphasizing its advantages, indications, and technical refinements.
Read More
Mechanisms and Management of Recurrences
Abhinav Sidana, MD, MPH, delves into the mechanisms and management of recurrences in patients undergoing focal therapy. This 17-minute presentation underscores the absence of a consistent surveillance strategy and advocates for a standardized approach, combining PSA tests, MRI, and biopsies to detect clinically significant cancer.
Dr. Sidana identifies factors such as patient selection, multifocal disease, and tumor biology as primary contributors to failures. His talk also addresses the challenges of inadequate margins and the spatial localization of lesions. Management strategies for recurrences focus on returning to foundational clinical assessments, considering patient life expectancy, comorbidities, cancer grade, and preferences. Cases illustrating success and challenges in treatment strategies reinforce the need for individualized patient care.
Dr. Sidana advocates for integrating biopsies and MRIs into surveillance protocols and highlights patient selection as pivotal to reducing therapy failures. This comprehensive analysis aims to refine focal therapy practices and improve patient outcomes.
Read More
Urologist Led Advanced Prostate Cancer Practice Tips, Tricks and Pitfalls
Aaron Berger, MD, delivers an in-depth discussion on the evolution and importance of urology-led advanced prostate cancer practices. In this 21-minute presentation, Dr. Berger traces the transformation of urological management from limited ADT to a multidisciplinary and pathway-driven approach today. Berger highlights the pivotal moments, such as the introduction of immunotherapy, effective oral options, and advancements in imaging guidelines, which allowed urologists to retain and expand their roles in treating advanced prostate cancer. He emphasizes the establishment of specialized clinics as critical, enabling comprehensive care through navigation systems, in-office dispensaries, and dedicated teams. Collaboration with radiation and medical oncologists is vital for managing complex cases and adopting innovations like PSMA-based therapies and triple therapy.
Read More
Genetic Testing in Prostate Cancer Management
Abhinav Sidana, MD, MPH, highlights the critical role of genetic testing in prostate cancer management, aiming to familiarize urologists with its fundamentals and practical application. In this 17-minute presentation, Dr. Saadana shares a detailed case study of a healthy 63-year-old male with prostate cancer, underscoring the importance of DNA damage repair pathway genes.
Dr. Sidana categorizes genetic mutations into germline mutations and somatic mutations. Both are essential in identifying actionable genetic alterations that guide early diagnosis, prognosis, and treatment. He emphasizes the prognostic implications of genetic testing in driving treatment strategies. Dr. Sidana highlights the utility of multi-gene panels that assess a broad range of cancers and the importance of genetic counseling in addressing the clinical and psychosocial aspects of testing. Current guidelines recommend testing for high-risk, metastatic, or familial prostate cancer cases.
Read More