Philip Kantoff, MD, presented “Convergent Therapeutics: Next-Generation Targeted Radiotherapies” during the 7th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 22, 2023.
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How to cite: Kantoff, Philip “Convergent Therapeutics: Next-Generation Targeted Radiotherapies.” September 22, 2023. Accessed Aug 2024. https://grandroundsinurology.com/convergent-therapeutics-next-generation-targeted-radiotherapies/
Convergent Therapeutics: Next-Generation Targeted Radiotherapies – Summary
Philip Kantoff, MD, explores the advancements in targeted radiotherapies, emphasizing their potential to revolutionize prostate cancer treatment. He introduces next-generation targeted radiotherapies, such as radioligand therapy, which utilize molecules designed to bind specifically to cancer cell markers, delivering lethal doses of radiation directly to the tumor cells. This approach minimizes damage to surrounding healthy tissues, a limitation of traditional radiotherapy.
Dr. Kantoff highlights convergent therapeutics, which combines targeted radiotherapy with other treatment modalities, including immunotherapy and conventional chemotherapy. Kantoff also addresses the challenges of implementing these advanced therapies in clinical practice.
The Global Summit on Precision Diagnosis and Treatment of Prostate Cancer is a unique multi-disciplinary forum organized to inform the key health care stakeholders about the emerging advances in clinical case and research and create a consensus-based vision for the future of precision care and educational and research strategy for its realization. The mission of the Summit is to fill the currently existing gap between the key experts of in vivo imaging, the world authorities in the in vitro fluid- and tissue-based molecular diagnostics, including genomics, and thought leaders in the development of novel observation strategies (e.g., active surveillance, or AS) and therapeutic interventions.
ABOUT THE AUTHOR
Philip W. Kantoff is a medical oncologist. He was appointed the Chief Executive Officer of Convergent Therapeutics on July 1, 2021. Prior to joining Convergent, Dr. Kantoff spent six years as Chairman of the Department of Medicine at Memorial Sloan Kettering Cancer Center, where he directed a department of approximately 500 physicians and physician-scientists, caring for cancer patients and developing improved testing and cancer therapies. He is the Emeritus Jerome and Nancy Kohlberg Chair in Medicine at Harvard Medical School. At Dana Farber Cancer Institute (DFCI), he was the Chief of the Solid Tumor Oncology Division, and he served as Director of the Lank Center for Genitourinary Oncology at the DFCI. In those positions, Dr. Kantoff created robust programs of clinical care and research as well as laboratory research. During this time, he served as a clinical researcher and principal investigator in significant trials devoted to the development of new therapeutic targets for men with advanced prostate cancer and, throughout his tenure at DFCI, he helped to set broad clinical research priorities.
Dr. Kantoff is a member of numerous professional societies and editorial boards, has written more than 500 articles and books and has lectured throughout the world. Among his significant accomplishments, Dr. Kantoff was honored with the Baruj Benacerraf Clinical Investigator Award from 1994 to 1997 and the Harvard Medical School Kantoff-Sang Lectureship Award from 2011 through the present time. He was also recognized with the first Prostate Cancer Foundation Mentor of Excellence Award and has been named to the second-year class of “Giants in Cancer Care.” He was inducted into the Association of American Physicians in 2017. Dr. Kantoff is board certified in internal medicine and medical oncology. He completed his research fellowship at the National Institutes of Health and his medical oncology fellowship at the Dana-Farber Cancer Institute.
