Adam Cole, USAF, Col. MD, presents “Digital Pathology for Detecting Prostate Cancer – TruCore Pathology.”
How to cite: Cole, Adam. “Digital Pathology for Detecting Prostate Cancer – TruCore Pathology.” February 19, 2025. Accessed Mar 2025. https://grandroundsinurology.com/digital-pathology-for-detecting-prostate-cancer-trucore-pathology/
Digital Pathology for Detecting Prostate Cancer – TruCore Pathology – Summary
Adam Cole, USAF, Col. MD, an anatomic and clinical pathologist and Chief Science Officer of TruCore Pathology, discusses how digital pathology transforms clinical practice, particularly in genitourinary pathology. In this 9-minute presentation, he introduces a fully digital lab solution that enhances tissue processing, tracking, and analysis.
How does digital pathology through TrueCore work?
As a urologist, utilizing a digital pathology report is emerging as an important part of your practice and prostate cancer detection.
From start to finish, genitourinary pathology has evolved with PathNet Labs digital pathology technology.
Using pre-labled biopsy boards, this technology provides immediate feedback to the quality of the prostate biopsy core and maintains orientation through the processing of the core. This allows for identification of the location of the cancer, if present. Biopsy tissue is also secured in the biopsy boards, decreasing damage during transport, and allowing the pathologist to see 15-20% more tissue than traditional biopsy methods.
Artificial Intelligence (AI) and Digital Pathology
Another advancement afforded by this technology is computer analyzed biopsy results instead of estimates of biopsy results by pathologists. Additionally, artificial intelligence is used as a “second set of eyes” in identifying cancer that may have been overlooked.
All of these advancements provide this digital pathology with one of the highest cancer detection rates in the United States, between 61-64%.
Example of AI assessing the prostate cancer biopsy.
What do the prostate biopsy pathology reports look like?
Dr. Cole explains what the pathology report looks like and how to utilize it.
Some highlights of the digital pathology report are the inclusion of critical comments, which can guide clinical decision making related to disease progression. If TruCore has worked collaboratively with the urologist to streamline the genomic ordering process, this area will also identify if a genomic test was ordered. This is also custom tailored to which genomic test you prefer and in which setting, like identifying patients who would benefit from treatment identifications like including androgen deprivation therapy (ADT) or which patients are a fit for active surveillance.
