Abhinav Sidana, MD, MPH, presented “Genetic Testing in Prostate Cancer Management” during the 2024 Frontiers in Oncologic Prostate Care and Ablative Local Therapy symposium on October 17, 2024, in San Diego, California.
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How to cite: Sidana, Abhinav. “Genetic Testing in Prostate Cancer Management.” October, 2024. Accessed Jan 2025. https://grandroundsinurology.com/genetic-testing-in-prostate-cancer-management/
Genetic Testing in Prostate Cancer Management – Summary
Abhinav Sidana, MD, MPH, highlights the critical role of genetic testing in prostate cancer management, aiming to familiarize urologists with its fundamentals and practical application. In this 17-minute presentation, Dr. Saadana shares a detailed case study of a healthy 63-year-old male with prostate cancer, underscoring the importance of DNA damage repair pathway genes.
Dr. Sidana categorizes genetic mutations into germline mutations and somatic mutations. Both are essential in identifying actionable genetic alterations that guide early diagnosis, prognosis, and treatment. He emphasizes the prognostic implications of genetic testing in driving treatment strategies. Dr. Sidana highlights the utility of multi-gene panels that assess a broad range of cancers and the importance of genetic counseling in addressing the clinical and psychosocial aspects of testing. Current guidelines recommend testing for high-risk, metastatic, or familial prostate cancer cases.
Frontiers in Oncologic Prostate Care and Ablative Local Therapy (FOCAL) is an outstanding program on prostate imaging, transperineal interventions, and ablative treatments for prostate cancer and benign prostatic hyperplasia. Bringing together community-based, academic, and industry partners, FOCAL offers lectures by world-renowned faculty and hands-on training workshops on in-office transperineal interventions, fusion-guided prostate ablation and state-of-the-art BPH management with novel technologies.
ABOUT THE AUTHOR
Abhinav Sidana, MD, MPH, is the Director of Prostate Cancer Focal Therapy, Director of GU Clinical Trials Urology Section, and Associate Professor of Surgery at the University of Chicago Medicine and Biological Sciences in Chicago, IL. Dr. Sidana earned his MD in 2007 from the All India Institute of Medical Sciences in New Delhi. Following this, he pursued a post-doctoral Fellowship in Urology at Johns Hopkins University School of Medicine in Baltimore, Maryland, during which he focused on translational projects relating to cancer immunotherapy and was instrumental in translating the preclinical work for a clinical trial studying cryo-immunotherapy. Subsequently, he completed his urology residency at the University of Cincinnati Medical Center and a urologic oncology fellowship at the National Cancer Institute of the National Institutes of Health. Dr. Sidana’s current clinical practice includes both surgical and non-operative management of prostate, kidney, ureteral, testicular, and bladder cancers. His research interests include functional prostate imaging, image-guided and focal treatments for prostate cancer, and clinical trials on novel treatments for urologic cancers.
