Kidney Cancer Journal | Volume 4, Issue 1
The Prognostic Value of DNA Methylation Markers in Renal Cell Cancer: A Systematic Review...
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Latest Videos
Managing a Clinical Research Program in 2020
Evan R. Goldfischer, MD, MBA, Co-Founding CEO and Founding Director of Research for Premier Medical Group of the Hudson Valley, discusses how those managing clinical research programs must adapt to new pressures in 2020. He notes that the increases in regulation and FDA oversight are challenges. He also details the necessary structure of research departments and processes for budget negotiation. By also describing possible pitfalls of clinical research programs, Dr. Goldfischer gives an encompassing overview of the process of clinical research program management.
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Recognizing and Managing the Side Effects of Androgen Deprivation Therapy
Alicia K. Morgans, MD, MPH, Associate Professor of Medicine in Hematology and Oncology at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, discusses the side effects of androgen deprivation therapy (ADT) and how urologists can mitigate them. She observes that up to 40% of non-metastatic prostate cancer patients are treated with ADT, and those patients tend to be older and have more comorbidities. Studies have suggested that comorbidities and advanced age interact with ADT to increase risk of cardiovascular disease and diabetes. ADT is also associated with increased risk of depression, cognitive changes, and possibly dementia, as well as greater frailty in patients. Urologists should be aware of these side effects so that they can assess their patients’ risk and plan accordingly with multidisciplinary teams to reduce mortality and morbidity and improve quality of life.
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Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline 2019
Jennifer T. Anger, MD, MPH, Associate Professor of Urology at Cedars-Sinai Medical Center, discusses recurrent uncomplicated urinary tract infections (UTIs) in women. Dr. Anger chairs the AUA committee on guidelines for infections, and she discusses the rationale behind recent changes to recommendations. She outlines how the thinking about recurrent infections has changed over time, and highlights the collateral damage that a one-size-fits-all antibiotic treatment can cause, noting that the new guidelines emphasize treating individual urinary cultures. She goes on to discuss patient profiles, common symptoms, and what the guidelines recommend for initial work-ups as well as treatments. Dr. Anger further delves into ways to prevent or decrease the risk of UTIs with antibiotic prophylaxis, along with the possible risks of doing so.
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Radiation Oncology Practice Management with COVID-19
Chaundre K. Cross, MD, a radiation oncologist with 21st Century Oncology in Naples, Florida, discusses the actions his practice has taken to maintain social distancing and safety standards during the COVID-19 crisis. Patients are encouraged to wait in their cars, only one patient is allowed to enter the practice at a time, and rooms and door knobs are sanitized between appointments. Dr. Cross notes that his practice is using telemedicine more frequently, and is deferring non-essential appointments. He concludes by observing that short-course radiation therapy (i.e. CyberKnife) is a particularly good option in the current moment.
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