Amy E. Krambeck, MD, presented “Morcellation and Potential HoLEP Complications” during the 44th Annual Ralph E. Hopkins Urology Seminar on February 5, 2025, in Jackson Hole, Wyoming.
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How to cite: Krambeck, Amy E. “Morcellation and Potential HoLEP Complications.” February 5, 2025. Accessed Mar 2025. https://grandroundsinurology.com/morcellation-and-potential-holep-complications-2/
Morcellation and Potential HoLEP Complications – Summary
Amy E. Krambeck, MD, discusses HoLEP morcellation and its associated complications, emphasizing procedural refinements and patient safety. In this 21-minute presentation, Dr. Krambeck details the morcellation process, highlighting the need for meticulous hemostasis and sufficient fluid inflow to prevent bladder injuries.
Dr. Krambeck shares techniques for managing resistant prostatic nodules, including strategic laser incisions and switching blades to facilitate tissue removal. She dispels concerns about cancer detection, citing studies that confirm HoLEP preserves tissue integrity comparable to TURP for histopathological analysis.
Complications are categorized into intraoperative, immediate postoperative, and long-term concerns, addressing capsular perforation, bladder injury, and fluid absorption. Dr. Krambeck presents data showing that transient urinary incontinence occurs in about 30% of cases postoperatively, but long-term rates remain low. She addresses erectile function preservation, noting that while retrograde ejaculation is expected, erectile function itself remains unchanged.
Dr. Krambeck highlights HoLEP’s utility in complex cases, affirming its safety, efficiency, and durability as a leading surgical option for BPH management.
About The 44th Annual Ralph E. Hopkins Urology Seminar:
The Ralph E. Hopkins Urology Seminar is a multi-day meeting focused on training urologists in the latest in assessing, diagnosing, and treating urologic conditions in the clinical setting. Updates are provided on urologic cancers, stone disease, urologic reconstruction, female urology, infertility, sexual function, emerging surgical techniques, and general urology. The 44th iteration of the meeting took place from February 5th to February 8th, 2025, in Jackson Hole, Wyoming.
For further educational activities from this conference, visit our collection page.
ABOUT THE AUTHOR
Amy E. Krambeck, MD, is a professor of urology at Northwestern University Feinberg School of Medicine in Chicago, Illinois. Dr. Krambeck earned her medical degree from the University of Missouri School of Medicine in Columbia. She completed her urology residency at the Mayo Clinic in Rochester, Minnesota, where she received extensive training and refined her surgical expertise. Following her residency, Dr. Krambeck pursued an endourology fellowship at the Methodist Institute for Kidney Stone Research in Indianapolis, Indiana.
Dr. Krameck specializes in the surgical and medical management of stone disease and benign prostatic hyperplasia (BPH), and she has alleviated the symptoms of many patients. Her research focuses on the pathogenesis of stone disease and novel treatments for urolithiasis during pregnancy.
Dr. Krambeck began her career as an endourologist at the Mayo Clinic's Department of Urology, where she demonstrated exceptional surgical skills and a strong commitment to patient care. In 2016, Dr. Krambeck joined Indiana University, where she led the benign urologic diseases division until 2020. Her leadership and expertise significantly advanced the division, offering patients innovative treatments for various urologic conditions.
Dr. Krambeck's dedication to her patients, extensive knowledge, and research contributions have established her as a leading figure in urology. She continues to influence the future of urologic care through her clinical excellence and academic endeavors.