Neda Hashemi, MD, presented “New Systemic Therapies for Advanced Urothelial Carcinoma” during the 28th Annual Innovations in Urologic Practice conference on September 22, 2024, in Denver, Colorado.
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How to cite: Hashemi, Neda. “New Systemic Therapies for Advanced Urothelial Carcinoma.” September 22, 2024. Accessed Nov 2024. https://grandroundsinurology.com/new-systemic-therapies-for-advanced-urothelial-carcinoma/
New Systemic Therapies for Advanced Urothelial Carcinoma – Summary
Neda Hashemi, MD, presents emerging systemic therapies for advanced bladder cancer, focusing on the transformative shifts since 2023. She highlights the pivotal role of recent ESMO findings in reshaping treatment paradigms, underscoring the shift from conventional platinum-based chemotherapy to more advanced immunotherapy-based approaches.
In this 18-minute presentation, Hashmi elaborates on the importance of the EV-302 trial, noting that these advances mark a turning point in treating metastatic bladder cancer. The CheckMate 901 study, though overshadowed by EV-302, also reveals promising results. Response rates for these patients suggest potential breakthroughs in disease management.
Hashemi acknowledges the complexity of managing treatment-related toxicities and emphasizes the importance of developing strategies to manage side effects effectively. Hashmi also touches on accessibility challenges outside the US, stressing the need for personalized approaches based on regional availability.
About The 28th Annual Innovations in Urologic Practice:
Presented by co-chairs Mohit Khera, MD, MBA, MPH, and Michael Coburn, MD, FACS, the Innovations in Urologic Practice conference provides a detailed review and commentary on multiple genitourinary and urologic diseases. Among the featured oncological topics are bladder cancer and immunotherapies, as well as upper tract cancer management, prostate cancer, including state-of-the-art imaging, focal therapy, and MRI. Experts also discuss new tools and techniques for nephrectomy and treating advanced renal cell carcinoma. In terms of general urological approaches, the conference also includes pelvic reconstruction and trauma; men’s health topics like male infertility, andrology, and sexual dysfunction; OAB and voiding dysfunctions; and ways to diagnose and treat infections in the urology patient.
For further educational activities from this conference, visit our collection page.