Jeremy Y.C. Teoh, MBBS, FRCSEd, FCSHK, FHKAM, presented “The Cardiovascular Effects of Orchiectomy Versus LHRH Agonists” for the Grand Rounds in Urology audience in February, 2020.
How to cite: Teoh, Jeremy Y.C. “The Cardiovascular Effects of Orchiectomy Versus LHRH Agonists” February, 2020. Accessed Dec 2024. https://grandroundsinurology.com/the-cardiovascular-effects-of-orchiectomy-versus-lhrh-agonists/
The Cardiovascular Effects of Orchiectomy Versus LHRH Agonists – Summary:
Jeremy Y.C. Teoh, MBBS, FRCSEd, FCSHK, FHKAM, Assistant Professor at the Chinese University of Hong Kong, outlines the increased risk of cardiovascular events associated with patients undergoing bilateral orchiectomy compared to patients treated instead with luteinizing hormone-releasing hormone (LHRH) agonists or antagonists. He discusses an important study that confirmed the increase in these events for men undergoing orchiectomy. Dr. Teoh continues by discussing another study, on which he was the lead investigator, that confirmed that orchiectomy conferred increased risk of ischemic stroke or myocardial infarction versus LHRH agonists in Chinese men. He concludes that the lower level of testosterone in men undergoing orchiectomy as well as the rise in follicle-stimulating hormone (FSH) levels may be contributing factors in the heightened cardiovascular risk of this procedure.
ABOUT THE AUTHOR
Dr. Jeremy Teoh is an Assistant Professor of Surgery at the Chinese University of Hong Kong. His primary areas of interest are prostate cancer and bladder cancer. He has published extensively on the adverse events related to androgen deprivation therapy, specifically from an Asian perspective. He is also a pioneer in Asia of transurethral en bloc resection of bladder tumors. He has published more than 100 articles in peer-reviewed journals, as well as 5 book chapters. He currently serves as the Director of the Lions Kidney Educational Centre and Research Foundation, as a faculty member of the Asian Urological Surgery Training & Education Group, and as a member of the Asian Robot-Assisted Radical Cystectomy Consortium.
