Alan H. Bryce, MD, presented “Updates in Advanced Prostate Cancer” during the 30th Annual Perspectives in Urology: Point-Counterpoint, on March 10, 2023, at Humphreys Half Moon Inn, San Diego, California.
How to cite: Bryce, Alan H. “Updates in Advanced Prostate Cancer.” March 10, 2023. Accessed Nov 2025. https://grandroundsinurology.com/updates-in-advanced-prostate-cancer/
Updates in Advanced Prostate Cancer – Summary
Alan H. Bryce, MD, reviews the current landscape of advanced prostate cancer treatment. Dr. Bryce begins by addressing the dwindling access to second-line treatment options as patients progress through therapy lines.
He then reviews findings from the STAMPEDE study, which explored the use of combination therapy involving ADT and abiraterone for high-risk prostate cancer patients. Dr. Bryce endorses this kind of combination therapy, highlighting its effect on overall survival rates.
Finally, Dr. Bryce touches on treatment intensification for patients with MHSC-9 positivity. Using a data-driven approach, he recommends combination therapy and the potential role of triplet regimens.
About the 30th Annual Perspectives in Urology: Point Counterpoint conference: Presented by Program Chair and Grand Rounds in Urology Editor-in-Chief E. David Crawford, MD, this conference brought together leading experts in urology, medical oncology, and radiation oncology to discuss and debate the latest topics in genitourinary cancers, primarily prostate cancer and bladder cancer. This interactive conference offered topical lectures, pro/con debates, interesting-case presentations, interactive panel discussions, and interactive audience and faculty networking.
ABOUT THE AUTHOR
Alan H. Bryce, MD, is a Medical Oncologist and Chief Clinical Officer at City of Hope in Phoenix, Arizona. Dr. Bryce holds an appointment as a Professor with the Department of Medical Oncology & Therapeutics Research and as a Professor of Molecular Medicine at Translational Genomics Research Institute (TGen), both a part of City of Hope.
