Mitchell R. Humphreys, MD, MPH, presented “The King of Enucleations: HoLEP” during the 31st Annual Perspectives in Urology: Point-Counterpoint, on October 18, 2024, in Scottsdale, Arizona.
How to cite: Humphreys, Mitchell R. “The King of Enucleations: HoLEP.” October 18, 2024. Accessed Mar 2025. https://grandroundsinurology.com/the-king-of-enucleations-holep/
The King of Enucleations: HoLEP – Summary
Mitchell R. Humphreys, MD, MPH, delves into the evolving landscape of benign prostatic hyperplasia (BPH) management, advocating for holmium laser enucleation (HoLEP) as a new gold standard. In this 15-minute presentation, Dr. Humphreys highlights the rising prevalence of BPH, accompanied by a decline in traditional surgeries, as minimally invasive procedures gain traction. Through detailed analysis, he underscores HoLEP’s versatility, demonstrating its efficacy across varying prostate sizes, patient ages, and clinical complexities.
Dr. Humphreys presents compelling data comparing HoLEP to traditional treatments such as transurethral resection of the prostate, showcasing superior functional outcomes, safety margins, and lower retreatment rates. Guidelines from the American Urological Association and European bodies endorse HoLEP as a highly effective approach. He emphasizes patient satisfaction, noting that surveys reveal higher quality of life and minimal regret among HoLEP recipients.
Dr. Humphreys urges a paradigm shift, positioning HoLEP as the definitive standard for BPH treatment due to its efficacy, safety, and patient-centered advantages.
About the 31st Annual Perspectives in Urology: Point Counterpoint conference: Presented by Program Chair and Grand Rounds in Urology Editor-in-Chief E. David Crawford, MD, this conference brought together leading experts in urology, medical oncology, and radiation oncology to discuss and debate the latest topics in genitourinary cancers, primarily prostate cancer and bladder cancer. This interactive conference offered topical lectures, pro/con debates, interesting-case presentations, interactive panel discussions, and interactive audience and faculty networking.
ABOUT THE AUTHOR
Mitchell Humphreys, MD, is a Professor and Chair of the Department of Urology at the Mayo Clinic in Scottsdale, Arizona. He holds dual appointments in the Department of Urology in the Mayo College of Medicine and in Clinical and Translational Sciences in the Mayo Graduate School. In addition, he serves as the Dean of the Mayo Clinic School of Continuous Professional Development and as the Endourology Fellowship Director. Dr. Humphreys completed his residency at the Mayo Clinic in Rochester and an Endourology and Stone Disease Fellowship at Indiana University. Since that time, he has been on staff at the Mayo Clinic in Arizona. His clinical focus is on surgical and metabolic stone disease, BPH (with a special focus on HoLEP), and minimally invasive GU oncology. In addition to the publication of over 100 peer-reviewed manuscripts and multiple book chapters, he is a journal editor and reviewer for several international urology journals. He is an active member of the Endourology Disease Group for Excellence (EDGE) research consortium. Outside of his work with the Mayo Clinic, he serves on the Board of Directors of GSD Healthcare, LLC, promoting basic healthcare initiatives in underserved and impoverished areas around the globe. He also serves as a member of the Columbia College Board of Trustees.
