Abhinav Sidana, MD, MPH

Abhinav Sidana, MD, MPH

University of Chicago Medicine and Biological Sciences

Chicago, IL

Abhinav Sidana, MD, MPH, is the Director of Prostate Cancer Focal Therapy, Director of GU Clinical Trials Urology Section, and Associate Professor of Surgery at the University of Chicago Medicine and Biological Sciences in Chicago, IL. Dr. Sidana earned his MD in 2007 from the All India Institute of Medical Sciences in New Delhi. Following this, he pursued a post-doctoral Fellowship in Urology at Johns Hopkins University School of Medicine in Baltimore, Maryland, during which he focused on translational projects relating to cancer immunotherapy and was instrumental in translating the preclinical work for a clinical trial studying cryo-immunotherapy. Subsequently, he completed his urology residency at the University of Cincinnati Medical Center and a urologic oncology fellowship at the National Cancer Institute of the National Institutes of Health. Dr. Sidana’s current clinical practice includes both surgical and non-operative management of prostate, kidney, ureteral, testicular, and bladder cancers. His research interests include functional prostate imaging, image-guided and focal treatments for prostate cancer, and clinical trials on novel treatments for urologic cancers.

Talks by Abhinav Sidana, MD, MPH

Mechanisms and Management of Recurrences

Mechanisms and Management of Recurrences

Posted by | Dec 2024

Abhinav Sidana, MD, MPH, delves into the mechanisms and management of recurrences in patients undergoing focal therapy. This 17-minute presentation underscores the absence of a consistent surveillance strategy and advocates for a standardized approach, combining PSA tests, MRI, and biopsies to detect clinically significant cancer.

Dr. Sidana identifies factors such as patient selection, multifocal disease, and tumor biology as primary contributors to failures. His talk also addresses the challenges of inadequate margins and the spatial localization of lesions. Management strategies for recurrences focus on returning to foundational clinical assessments, considering patient life expectancy, comorbidities, cancer grade, and preferences. Cases illustrating success and challenges in treatment strategies reinforce the need for individualized patient care.

Dr. Sidana advocates for integrating biopsies and MRIs into surveillance protocols and highlights patient selection as pivotal to reducing therapy failures. This comprehensive analysis aims to refine focal therapy practices and improve patient outcomes.

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Genetic Testing in Prostate Cancer Management

Genetic Testing in Prostate Cancer Management

Posted by | Dec 2024

Abhinav Sidana, MD, MPH, highlights the critical role of genetic testing in prostate cancer management, aiming to familiarize urologists with its fundamentals and practical application. In this 17-minute presentation, Dr. Saadana shares a detailed case study of a healthy 63-year-old male with prostate cancer, underscoring the importance of DNA damage repair pathway genes.

Dr. Sidana categorizes genetic mutations into germline mutations and somatic mutations. Both are essential in identifying actionable genetic alterations that guide early diagnosis, prognosis, and treatment. He emphasizes the prognostic implications of genetic testing in driving treatment strategies. Dr. Sidana highlights the utility of multi-gene panels that assess a broad range of cancers and the importance of genetic counseling in addressing the clinical and psychosocial aspects of testing. Current guidelines recommend testing for high-risk, metastatic, or familial prostate cancer cases.

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Rectal Spacer

Rectal Spacer

Posted by | Dec 2024

Abhinav Sidana, MD, MPH, addresses the role of rectal spacers in reducing gastrointestinal toxicity during prostate radiation therapy. The 11-minute presentation discusses three types of FDA-approved rectal spacers: Polyethylene Glycol-Based Spacers (SpaceOAR), Hyaluronic Acid-Based Spacers, and Balloon Spacers (BioProtect).

Dr. Sidana shares images to illustrate the procedural steps for patient preparation, numbing, hydro-dissection, and accurate spacer placement, guided by imaging. Post-procedure imaging, such as MRI or CT scans, can be used to confirm correct placement.

Dr. Sidana also discusses potential complications, including minor pain and rectal fullness and rare instances of severe outcomes like rectourethral fistulas or sepsis. He notes, however, that these devices generally have a favorable safety profile.

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