Oklahoma City Archives

Blue Light vs. White Light Cystoscopy for NMIBC

Posted by Sanjay G. Patel, MD | Jul 2021

Sanjay G. Patel, MD, Assistant Professor of Urology at the University of Oklahoma in Oklahoma City, considers the benefits of blue light versus white light cystoscopy for non-muscle-invasive bladder cancer (NMIBC) imaging. He goes over the importance of good imaging in minimizing progression and recurrence, then looks at the evidence behind blue light cystoscopy, highlighting the improved rates of detection of Ta, T1, and CIS tumors compared to white light cystoscopy. Dr. Patel also notes that these improved rates of detection appear to translate to reduced rates of recurrence and progression as well as increased time to recurrence and progression. He concludes by looking at guideline recommendations on when to use blue light cystoscopy.

A Review of AUA / SUO / ASTRO Guidelines for MIBC

Posted by Michael S. Cookson, MD, MMHC | Jun 2021

Michael S. Cookson, MD, MMHC, Professor and Chairman of the Department of Urology at the University of Oklahoma Health Sciences Center, summarizes the updated AUA/SUO/ASTRO guideline for the treatment of muscle-invasive bladder cancer (MIBC), a particularly deadly and difficult-to-treat disease. He explains the purpose and methodology of the guideline, summarizes its contents, and makes a note of recent and ongoing research in the areas of chemotherapy, extended pelvic lymphadenectomy, and bladder preservation that may change the guidelines in the future.

Changing Landscape of mHSPC: New Approaches to an Old Problem

Posted by Michael S. Cookson, MD, MMHC | Jun 2020

Michael S. Cookson, MD, MMHC, Professor and Chairman of the Department of Urology at the University of Oklahoma Health Sciences Center in Oklahoma City, gives an overview of the changing landscape of metastatic hormone-sensitive prostate cancer (mHSPC). He reviews the different treatment strategies that have undergone testing over the last eight decades, noting that although treatment options have progressed, there is still work to be done to continue improving results. He presents the findings of key studies that look to improve survival through the use of more potent androgen-targeting techniques, among other cutting edge treatments. These new treatments show promising results in lowering risk of spread and death, bolstering Dr. Cookson’s key point: that the landscape is rapidly changing, and urologists need to adapt quickly.

Genetic Testing in Prostate Cancer

Posted by Mohammad O. Ramadan, MD | Jun 2020

Mohammad O. Ramadan, MD, discusses the importance of genetic testing for prostate cancer screening, diagnosis, and treatment. He notes that there is currently a professional practice gap in this area, even as genetic testing becomes more widely available. Studies suggest that approximately 17% of prostate cancer patients are biomarker positive, and therefore may benefit more than other patients from treatments like PARP inhibitors. Research like this has led the NCCN to recommend germline genetic testing for all men with high-risk, very-high-risk, regional, or metastatic prostate cancer. With this guideline in place, urologists will have to quickly figure out how to provide widespread testing, and may have to partner with geneticists.

Management of High-Grade Upper Tract Urothelial Cell Carcinoma

Posted by Brian W. Cross, MD | Mar 2020

Brian W. Cross, MD, Assistant Professor of Urology at the University of Oklahoma College of Medicine, discusses chemotherapy options in patients undergoing nephroureterectomy (NU). He goes on to discuss the advantages of perioperative chemotherapy following NU, the role of neoadjuvant chemotherapy in patients with high-risk upper tract urothelial carcinoma prior to NU, and surgical techniques for the management of the distal ureter during NU.