Video Archives

Cannabis Use and Male Reproductive Health: Who Knew?

Posted by Thomas J. Walsh, MD, MBA, MS | Aug 2024

Thomas J. Walsh, MD, MBA, MS, discusses the impact of habitual cannabis use on male fertility and reproductive health. He begins by establishing the current landscape and demographics of cannabis users globally, and the mechanisms behind its popularity as a recreational and medicinal substance.

Dr. Walsh then discusses emerging data on the impacts of cannabis on male fertility. He explores the deleterious influence of cannabis on Anandamide (nM) production and sperm morphology.

Dr. Walsh concludes with an examination of his own prospective analysis on the fertility of men presenting at his clinic for reproductive issues after current or past cannabis use. He underscores the importance of counseling patients using the available evidence, and strongly recommends against cannabinoid use while planning for a family.

Diagnosing Renal Masses: Do Advanced Imaging Techniques and Biomarkers Play an Important Role?

Posted by Justin J. Badal, MD | Aug 2024

Justin J. Badal, MD, explores the prognostic and predictive value of biomarkers and imaging in the diagnosis of renal conditions. He begins by reviewing the history of biomarkers and their use in the diagnosis and treatment of renal conditions.

Dr. Badal then addresses potential predictive uses of renal condition biomarkers. He presents data from the Checkmate 025 and INmotion150 studies which did not support the predictive value of certain prognostic biomarkers, and future directions for identifying predictive biomarkers.

Dr. Badal concludes with an overview of the effectiveness of combining biomarker detection with imaging technologies to improve prognostic and predictive accuracy. He presents data from the ZIRCON study, and discusses the potential integration of AI in biomarker detection.

High Resolution Micro-Ultrasound: Going Beyond MRI

Posted by Laurence Klotz, MD, FRCSC | Jul 2024

Laurence Klotz, MD, FRCSC, illustrates the value of high resolution micro-ultrasound over that of multiparametric MRI (mpMRI) in prostate cancer staging and diagnosis. He begins by reviewing the history, strengths, and limitations of mpMRI, and he presents his own history with high resolution micro-ultrasound.

Dr. Klotz then explains the differences between high resolution micro-ultrasound and conventional ultrasound. He compares the sensitivity, precision, and accuracy of high resolution micro-ultrasound against those of mpMRI and conventional ultrasound.

Dr. Klotz concludes by examining the efficacy of combining mpMRI and high resolution micro-ultrasound for prostate cancer diagnosis and staging. He presents data from ongoing trials supporting the use of high resolution micro-ultrasound as a complement to mpMRI.

The Artificial Urinary Sphincter in Complex Situations

Posted by Margit Fisch, MD, FEAPU, FEBU | Jul 2024

Margit M. Fisch, MD, FEAPU, FEBU, discusses the use of artificial urinary sphincters for the management of complex male Stress Urinary Incontinence (SUI) cases. She begins with a review of the body of data supporting the success rates of artificial urinary sphincters in straightforward cases.

Dr. Fisch then addresses the complications and their impact on the success of artificial urinary sphincter implantation, including:

Comorbidities
Post-Irradiation Status
Post-Urethroplasty Status
Reimplantation
Use of Transcorporal Cuff

For each of these complications, Dr. Fisch demonstrates strategies and best practices for minimizing their impact on surgical and patient outcomes.

The Future of AI in Pathologic Evaluation of Prostate Cancer

Posted by Francisco G. La Rosa, MD | Jul 2024

Francisco G. LaRosa, MD, FCAP, explores possible applications for artificial intelligence (AI) in prostate cancer detection and treatment. He begins by outlining the potential benefits of AI in prostate cancer evaluation.

Dr. LaRosa then discusses the technological innovations which allowed AI to be incorporated as a tool in prostate cancer detection. He presents current examples of AI being used in prostate cancer screening.

However, Dr. LaRosa concludes by cautioning against relying on AI He outlines current issues with machine-vision capabilities, detection models, unclear objectives, and contaminated training data.