Mark A. Moyad, MD, MPH, presented “Diet Only and Prostate Cancer ” during the 31st International Prostate Cancer Update in July 2021 in Snowbird, Utah.
How to cite: Moyad, Mark A. “Diet Only and Prostate Cancer.” July 2021. Accessed Nov 2024. https://grandroundsinurology.com/diet-only-and-prostate-cancer/
Diet Only and Prostate Cancer – Summary
Mark A. Moyad, MD, MPH, Jenkins/Pokempner Director of Preventive/Complementary and Alternative Medicine (CAM) in the University of Michigan Department of Urology, reviews several trials showing the impact of dieting to lose weight on cancer and cancer recurrence, focusing particularly on prostate cancer. He begins with a discussion of the WINS and WHEL trials on dietary changes and breast cancer which, together, found that improving the quality of a diet does not appear to have a profound impact on cancer or recurrence, but that while dieting with a focus on weight loss reduces recurrence rates and establishes a number needed to treat (NNT) of 38. Dr. Moyad continues with preliminary data from the Success-C trial, a study with the goal of using caloric reduction and exercise to reduce weight and is showing that those who adhere to the lifestyle changes have significantly improved rates of disease-free survival. He then looks at the POUNDS LOST trial, whose results suggest that, regardless of the weight-loss process, if weight loss occurs then health benefits can be reached. Dr. Moyad also discusses the CALERIE and MEAL trials. The former study had patients cut back calories by 13% on average and showed that slow methodical weight-loss creates heart-healthy metabolic and numeric changes. The latter had active surveillance participants significantly increase their vegetable intake but has not currently found any remarkable differences between the control and intervention groups. He also discusses the latest impressive vegan randomized study, which demonstrated dramatic weight loss of 14 lbs over 16 weeks utilizing a practically unrecognized caloric reduction strategy. He summarizes the results of over 85 studies on excess alcohol and adipose tissue which support the idea that both are carcinogens and are shown to reduce the efficacy of some drugs. Dr. Moyad also observes that data on lycopene shows that increased fruit and vegetable intake is supportive of overall heart health, how recent research shows no clear cause and effect link between cancer and vitamin D or omega 3s, and how the MANSMED trial shows the benefit of using metformin in addition to standard-of-care therapy. He concludes by observing that heart-healthy calorie restriction programs that encourage adherence, happiness, and healthy outcomes are good for managing prostate cancer, and by briefly discussing the potential of semaglutide injections to help some patients lose weight.
About The 31st Annual International Prostate Cancer Update:
The International Prostate Cancer Update (IPCU), founded in 1990, is a multi-day CME conference focused on prostate cancer treatment updates with expert, international faculty. It is led by expert physicians and is designed for urologists, medical oncologists, radiation oncologists, and other healthcare professionals involved in the diagnosis and treatment of prostate cancer. Dr. Moyad delivered this educational activity during the 31st iteration of the meeting in July 2021 in Snowbird, Utah.
ABOUT THE AUTHOR
Dr. Moyad’s mission is to promote a greater attention to comprehensive lifestyle changes to improve overall mental, physical, and spiritual wellness along with contributing to more objective education on dietary supplements, OTC, and other potential health options. This has been the focus of his research, writings, and lectures his entire career. He occupies an endowed position, which was originally created and funded by the individuals he has empowered over the past 25+ years. He is the Jenkins/Pokempner Director of Complementary and Alternative Medicine (CAM) Education at the University of Michigan Medical Center in the Department of Urology. This was one of the first endowments of its kind created for a doctor at a major medical center. Dr. Moyad has always considered himself to be first, and foremost, a public health educator with an expertise in clinical/medical epidemiology. Dr. Moyad received his medical education from the University of South Florida College of Public Health and the Wayne State University School of Medicine. He is the primary author of over 150 medical journal publications on lifestyle changes and supplements, the past Editor-in-Chief of the medical journal Seminars in Preventive & Alternative Medicine, past CAM course director for a variety of medical societies, continues to be a guest editor and provide peer review for multiple medical journals, and he has given thousands of lectures around the world to the public and health care professionals in virtually every medical specialty and major medical center. Dr. Moyad is the author or co-author of 15 academic and consumer books, and now interviews other health experts on a variety of global wellness topics to enhance notable health care professional and patient education sources. He is also honored to be the moderator of one of the largest patient conferences held twice a year in Los Angeles, California, and has provided educational clinical research updates for the last 20+ years to health care professionals and national patient advocacy groups.
