Sijo Parekattil, MD, presented “Industry Perspective: Image-Guided Focal Laser Ablation for Prostate Cancer with CLS-TRANBERG” for the Grand Rounds in Urology audience on November 9, 2023.

How to cite: Parekattil, Sijo. Industry Perspective: Image-Guided Focal Laser Ablation for Prostate Cancer with CLS-TRANBERG.” November 9, 2023. Accessed Jul 2024.

Industry Perspective: Image-Guided Focal Laser Ablation for Prostate Cancer with CLS-TRANBERG – Summary

In this Industry Perspective, Sijo Parekattil, MD, reviews how the CLS-TRANBERG system is used for image-guided focal laser ablation for prostate cancer in his practice. Dr. Parekattil first explains the importance of finding a safe method for treating localized prostate cancer, highlighting the prediction that 1.7 million men will be diagnosed with localized prostate cancer in 2040. He then analyzes two initial treatments currently in use, Active Surveillance and Radical Therapy, pinpoints issues with these methods, including the risk of missing growth and the onset of impotence and incontinence, and explains that the CLS-TRANBERG system combines the best of both treatments while avoiding their risks. 

Dr. Parekattil explores additional patient benefits, like quicker recovery, fewer side effects, and increased quality of life. He then highlights the system’s efficiency, noting that it can be performed in small, office-based settings. Dr. Parekattil further evaluates CLS-TRANBERG by listing image modalities it can be paired with, such as MRI and ultrasound. He notes that ultrasound even allows for real-time observation of tissue changes, increasing the operator’s ability to perform precise ablation. He also stresses the safety of the system by reviewing temperature probes and the avoidance of damaging surrounding organs. 

Additionally, Dr. Parekattil emphasizes the lack of a need for a cooling loop in the CLS-TRANBERG system, adding ease to the procedure. He transitions to a discussion of the patient experience, presenting a patient testimonial that expresses a lack of discomfort and side effects. Dr. Parekattil completes his discussion by reviewing practice benefits and the consistent drop in PSA levels experienced by his patients after the CLS-TRANBERG procedure. Ultimately, Dr. Parekattil encourages urologists to consider this system as an option in initial prostate cancer treatment.


Dr. Sijo Parekattil is Director of Avant Concierge Urology, Winter Garden, FL and an Associate Professor of Urology at the University of Central Florida (UCF). He was an Electrical Engineer (University of Michigan) prior to his medical training and thus has interests in surgical techniques incorporating technology, robotics and microsurgery. He completed his urology residency training at Albany Medical Center and then went onto complete dual fellowship training from the Cleveland Clinic Foundation, Cleveland in Laparoscopy/Robotic Surgery and Microsurgery/Male Infertility. He is one of the only urologists in the country with this type of dual fellowship training background.

Dr. Parekattil has received numerous awards including two Annual Innovator Awards from the Cleveland Clinic Foundation and the Golden Garland Award in Medicine in 2012. He has published several articles in the field of robotic microsurgery and microsurgery. He is an editor on a few textbooks on Male Infertility and a surgical textbook on Robotic Microsurgery. He has performed some pioneering work in the arena of microsurgery and has performed well over 3000 such procedures. He has developed a multi-disciplinary program dedicated to the treatment of male infertility and groin/testicular pain. He is also a Visiting Professor at the University of Zambia, Lusaka, Africa.

He is one of the founding Board members of the Robotic Assisted Microsurgical & Endoscopic Society (RAMSES), a group focused on the evidence-based development of tools and platforms for robotic-assisted microsurgery, and the International Microsurgical Simulation Society (IMSS), a group focused on developing more standardized and effective microsurgical training techniques. He is on the foundation board for the Florida Polytechnic University, Lakeland, FL, and an Executive Board Member of the Florida Urological Society.