Sadhna Verma, MD, FSAR, presented “Interpretation of Post Focal Therapy Imaging Target and Pifab” during the 2024 Frontiers in Oncologic Prostate Care and Ablative Local Therapy symposium on October 17, 2024, in San Diego, California.
>
How to cite: Verma, Sadhna. “Interpretation of Post Focal Therapy Imaging Target and Pifab.” October, 2024. Accessed Jan 2025. https://grandroundsinurology.com/interpretation-of-post-focal-therapy-imaging-target-and-pifab/
Interpretation of Post Focal Therapy Imaging Target and Pifab – Summary
Sadhna Verma, MD, MBA, FSAR, explores advancements in imaging and reporting for post-focal therapy in prostate cancer, highlighting the emergence of two scoring systems, TARGET and PI-FAB. This 16-minute presentation provides an overview of expected multiparametric MRI findings at different post-treatment intervals, describing immediate changes like coagulative necrosis and late findings such as fibrosis and scarring.
Dr. Verma introduces TARGET, a consensus-based system focusing on MRI timing, technical parameters, and interpretation. The PI-FAB system, developed from expert opinion, similarly prioritizes dynamic contrast imaging. Comparative examples illustrate their application.
Preliminary studies reveal moderate inter-reader agreement for both systems, though sensitivity and specificity vary, underscoring the importance of experience in interpretation. Despite promising results, the presenter stresses the need for validation through large, multicenter cohorts and integration with molecular imaging to enhance diagnostic accuracy.
Frontiers in Oncologic Prostate Care and Ablative Local Therapy (FOCAL) is an outstanding program on prostate imaging, transperineal interventions, and ablative treatments for prostate cancer and benign prostatic hyperplasia. Bringing together community-based, academic, and industry partners, FOCAL offers lectures by world-renowned faculty and hands-on training workshops on in-office transperineal interventions, fusion-guided prostate ablation and state-of-the-art BPH management with novel technologies.
ABOUT THE AUTHOR
Sadhna Verma, MD, FSAR, is a Professor of Radiology, Radiation Oncology and Urology at University of Cincinnati Medical Center. She is also the Director of Prostate Imaging Program, Associate Chair of Quality and Performance Improvement at the Prostate Cancer Midwest Center of Excellence, as well as the Director Prostate Cancer Imaging Program at the U.S. Department of Veterans Affairs.
Dr. Verma completed a diagnostic radiology residency at the University of Cincinnati and a fellowship in Abdominal Imaging from the Johns Hopkins Medical Center. Dr. Verma’s clinical expertise and current clinical research interests are in genitourinary MR imaging. She has published extensively and delivered numerous invited lectures on the topic of prostate MRI and MR-Guided Interventional Procedures.
