E. David Crawford, MD, presented “Patient’s Journey: Experience with mCRPC and the Lutetium (Pluvicto) Shortage” for the Grand Rounds in Urology audience in April 2023.

How to cite: Crawford, E. David. “Patient’s Journey: Experience with mCRPC and the Lutetium (Pluvicto) Shortage” April 2023. Accessed Jul 2024. https://grandroundsinurology.com/patients-journey-experience-with-mcrpc-and-the-lutetium-pluvicto-shortage/

Patient’s Journey: Experience with mCRPC and the Lutetium (Pluvicto) Shortage – Summary

E. David Crawford, MD, Editor-in-Chief of Grand Rounds in Urology, interviews his patient Lon, as well as Lon’s partner Kacy, about their treatment journey since Lon was diagnosed with advanced prostate cancer in 2018, as well as how the lutetium (Pluvicto) shortage has necessitated changes to his treatment plan. Lon first saw Dr. Crawford in 2018 and was diagnosed with advanced metastatic prostate cancer and has responded well to treatments in the ensuing years, including chemotherapy with docetaxel, ADT, radium 223, and sipuleucel-t. Lon discusses how he has undergone PSMA scans this year, which showed metastases in his liver, and while he would normally be a candidate for lutetium, the shortage in production has required an alternate treatment plan with cabazitaxel until it is available. Kacy talks about how amazed she is at the number of new treatments that have become available since his initial diagnosis, as well as how his positive response to all of them has allowed him to maintain a high quality of life, other than occasional fatigue, allowing them to keep up a frequent travel schedule and continue to living life at its fullest.

For more information on the lutetium (Pluvicto) shortage, see Dr. Crawford’s discussions with Edwin M. Posadas, MD, as well as Alan H. Bryce, MD, and Bryan A. Mehlhaff, MD.

ABOUT THE AUTHOR

Researcher-physician E. David Crawford, MD, has devoted his career in medicine to educating the public about men's health issues and finding effective techniques and procedures to address prostate cancer, the most common malignancy affecting men in the United States.

He is currently a Professor of Urology and Jack A. Vickers Director of Prostate Research at the University of California, San Diego. Dr. Crawford received his medical degree from the University of Cincinnati and his postgraduate training included an internship and residency in urology at the Good Samaritan Hospital in Cincinnati. He subsequently completed a genitourinary cancer fellowship at the University of California Medical Center in Los Angeles.

Dr. Crawford is an internationally recognized expert in benign prostate hypertrophy, urologic cancers, and in particular, prostate cancer. He has conducted research in the treatment of advanced bladder cancer, metastatic adenocarcinoma of the prostate, hormone-refractory prostate cancer, and other areas of urological infections and malignancies. He has authored or coauthored over 810 scientific articles, has published seven textbooks, authored over 60 book chapters, and provided more than 2,200 educational talks for patients and physicians.

In an effort to raise public awareness about prostate health, Crawford in 1989 founded the Prostate Conditions Education Council (PCEC). The non-profit organization is comprised of a consortium of leading physicians, health educators, scientists, and men's health advocates. PCEC's advocacy for free or low-cost prostate screening has affected the lives of millions of American men. He currently chairs the PCEC.

Crawford is an active member of many national and international organizations, including the American Society of Clinical Oncology, the American Urological Association (AUA), and the American Association for the Advancement of Science. Within the AUA, he has been a member of the Committee to Study Urologic Research Funding and the prostate cancer clinical trials subcommittee. Crawford served on the board of governors, the scientific advisory board of the Southwest Oncology Group, and was chairman of the Genitourinary Cancer Committee for 27 years. This group is the largest clinical trials group in the world.

Crawford's involvement in the national prostate cancer arena has been widely recognized. He has received many honors and awards, including the CAP Cure Annual Award for Scientific Presentation in 1999 In 1997, he was presented with a 'Freddie Award" at the AMA International Health and Medical Film Competition for the program, ITV: The Cutting Edge Medical Report (Prostate Cancer: Understanding, Diagnosing, and Defeating), which Crawford hosted with special guest, retired General Norman Schwarzkopf.

Crawford again won a prestigious 'Freddie Award" 5 years ago... He is a member of Best Doctors of America and was named Healthcare Provider of the Year in the Denver Metro area by the Denver Business Journal.

He has been recognized as one of the Best Doctors of America for the past two decades and is recognized as one of the top 20 urologists in the country, for men, by Men’s Health Magazine. In 2018 he received the honor of being named the Distinguished Alumnus of the Year from the University of Cincinnati School of Medicine. In May of 2019, he received the Presidential citation from the American Urological Association recognizing for his “tireless role in genitourinary cancer research that has benefited countless urologic cancer patients.” He accepted the position of Editor in Chief of Grand Rounds in Urology in June of 2019. In 2021, he was the recipient of the Merle Stringer, M.D. annual award for excellence in medicine by the Florida State Medical Association.