Thomas M. Wheeler, MD, presented “Prostate: Anatomic Considerations” during the 7th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer on September 21, 2023.
How to cite: Wheeler, Thomas M. “Prostate: Anatomic Considerations.” September 21, 2023. Accessed Jul 2024. https://grandroundsinurology.com/prostate-anatomic-considerations/
Prostate: Anatomic Considerations – Summary
Thomas M. Wheeler, MD, presents anatomic considerations relating to the prostate and prostate cancer for clinicians. He begins by illustrating why prostate cancer rarely metastasizes via the neighboring rectum, usually spreading to the rest of the body via the neurovascular bundle.
Dr. Wheeler then presents a few examples of prostate cancer, noting that most prostate cancer is multifocal. He presents multiple cross-sections of prostate cancer to illustrate the differences between multifocal cancer, index cancer, and large volume unifocal prostate cancer.
Dr. Wheeler concludes by reviewing the history of differentiating prostate zones, tumor volume and Gleason scores in prostate cancer, and what they indicate in patient prognosis. He notes that levels of capsular invasion, perineural invasion diameter, and presence of intraductal carcinoma are all significant prognostic indicators.
The Global Summit on Precision Diagnosis and Treatment of Prostate Cancer is a unique multi-disciplinary forum organized to inform the key health care stakeholders about the emerging advances in clinical case and research and create a consensus-based vision for the future of precision care and educational and research strategy for its realization. The mission of the Summit is to fill the currently existing gap between the key experts of in vivo imaging, the world authorities in the in vitro fluid- and tissue-based molecular diagnostics, including genomics, and thought leaders in the development of novel observation strategies (e.g., active surveillance, or AS) and therapeutic interventions.
ABOUT THE AUTHOR
Thomas M. Wheeler, MD, is the Head of Surgical Pathology and Cytopathology at Sagis Diagnostic Pathology in Houston, Texas. Dr. Wheeler earned his medical degree from Baylor College of Medicine and completed his residency and fellowship at Baylor College of Medicine’s affiliate hospital. He is certified in anatomic and clinical pathology and cytopathology by the American Board of Pathology. In addition to surgical pathology and cytopathology, he specializes in urologic and thyroid diagnostics.
Dr. Wheeler has published over 350 works and is interested in clinicopathological correlations, including evaluating biomarkers in prostate carcinoma. Dr. Wheeler served as a member of the Board of Governors for the College of American Pathologists from 2003-2009. He also served as the President of the Texas Society of Pathologists, the Texas Society of Cytology, and the Houston Society of Clinical Pathologists. His previous positions include serving as Senior Vice Chair for the W.L. Moody, Jr. Faculty Practice Pathology Group, Distinguished Emeritus Professor and Immediate Past Chair of the Department of Pathology & Immunology at Baylor College of Medicine, and Member of the Dan L. Duncan Comprehensive Cancer Center at Baylor College of Medicine.
