Leonard G. Gomella, MD, FACS, presented “Role of Precision Medicine in the Diagnosis and Management of Prostate Cancer” during the 24th Future Directions in Urology Symposium in August 2024 in Colorado Springs, Colorado.
How to cite: Gomella, Leonard G. “Role of Precision Medicine in the Diagnosis and Management of Prostate Cancer.” August 2024. Accessed Nov 2025. https://grandroundsinurology.com/role-of-precision-medicine-in-the-diagnosis-and-management-of-prostate-cancer/
Role of Precision Medicine in the Diagnosis and Management of Prostate Cancer – Summary
Leonard G. Gomella, MD, FACS explores the rapid evolution of precision medicine, particularly in the context of prostate cancer, highlighting the shift from a one-size-fits-all approach to more personalized, genomics-based strategies. Precision medicine aims to tailor treatment and prevention strategies to the individual, moving beyond traditional methods to incorporate genetic, genomic, and molecular data.
In this 12-minute presentation, Dr. Gomella discusses key components of precision medicine in prostate cancer, including biomarkers, risk prediction, stratification, and drug repurposing. Advances in imaging technologies, such as improved MRI and ultrasound, as well as liquid biopsies, allow for deeper insights beyond histology, utilizing biomarkers, RNA tumor markers, and detailed genomic analysis. These innovations facilitate a more precise understanding of individual patients’ cancer profiles, helping to refine screening and treatment decisions.
Further, he asserts that precision medicine has substantially impacted the management of advanced prostate cancer, with targeted therapies tailored to genetic mutations and molecular characteristics. This approach exemplifies the precision targeting of treatments based on individual tumor profiles, optimizing outcomes and minimizing unnecessary interventions.
The Future Directions in Urology Symposium (FDUS) is an annual urology think tank and non-CME educational summit that brings together industry figures and experts to discuss the current state of genitourinary care and define future directions in treatment. Dr. Dreicer delivered this educational activity during the 24th iteration of the meeting in August 2024 in Colorado Springs, Colorado.
ABOUT THE AUTHOR
Leonard G. Gomella, MD, FACS, completed medical school and general surgery and urology training at the University of Kentucky in Lexington. After a urologic oncology fellowship in the surgery branch of the National Cancer Institute, National Institutes of Health in Bethesda, Maryland. Dr. Gomella is currently the Bernard W. Godwin, Jr. Professor of Prostate Cancer, Chairman of the Department of Urology, Senior Director of Clinical Affairs for the Sidney Kimmel Comprehensive Cancer Center, and the Enterprise VP of Urology at the Jefferson Health System, at Thomas Jefferson University in Philadelphia, Pennsylvania.
