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2024

Pathological Aspects of BPH, Prostatitis, and Other Painful Co-Occurrences

Francisco G. LaRosa, MD, FCAP, explores the pathology of benign prostatic hyperplasia (BPH), prostatitis, and associated urological conditions. He begins by reviewing the pathophysiology of BPH, presenting examples of usual and specific patterns of BPH and their progression.

Transitioning to prostatitis, Dr. LaRosa examines acute and chronic prostatitis. He highlights the mechanisms behind its close association with BPH, despite its frequent misdiagnosis and mismanagement in BPH patients.

Dr. LaRosa concludes by providing examples of other non-cancerous co-occurrences which can be discovered after prostate biopsy. He focuses on fibromas, thromboembolisms, and calcification.

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YouTube Surgeons – The Role of Video Learning in Urology

Ryan P. Terlecki, MD, FACS, explores current resources for lifelong learning and metrics for measuring success for urologic surgeons. He begins by reviewing the skills and technology-based challenges facing urologists today.

Dr. Terlecki explores the evolution of expectations and goals of medical education across generations. He reviews the history of surgical training from the Halsted Model to present day educational standards for continuous professional education, including the increasing ubiquity of video in daily practice.

Dr. Terlecki concludes by highlighting the benefits and dangers of using videos to train, provided that feedback from an expert source is incorporated in the training. He illustrates different models for trainees and established surgeons to improve their performance using a combination of expert insights and video analysis.

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Cannabis Use and Male Reproductive Health: Who Knew?

Thomas J. Walsh, MD, MBA, MS, discusses the impact of habitual cannabis use on male fertility and reproductive health. He begins by establishing the current landscape and demographics of cannabis users globally, and the mechanisms behind its popularity as a recreational and medicinal substance.

Dr. Walsh then discusses emerging data on the impacts of cannabis on male fertility. He explores the deleterious influence of cannabis on Anandamide (nM) production and sperm morphology.

Dr. Walsh concludes with an examination of his own prospective analysis on the fertility of men presenting at his clinic for reproductive issues after current or past cannabis use. He underscores the importance of counseling patients using the available evidence, and strongly recommends against cannabinoid use while planning for a family.

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Diagnosing Renal Masses: Do Advanced Imaging Techniques and Biomarkers Play an Important Role?

Justin J. Badal, MD, explores the prognostic and predictive value of biomarkers and imaging in the diagnosis of renal conditions. He begins by reviewing the history of biomarkers and their use in the diagnosis and treatment of renal conditions.

Dr. Badal then addresses potential predictive uses of renal condition biomarkers. He presents data from the Checkmate 025 and INmotion150 studies which did not support the predictive value of certain prognostic biomarkers, and future directions for identifying predictive biomarkers.

Dr. Badal concludes with an overview of the effectiveness of combining biomarker detection with imaging technologies to improve prognostic and predictive accuracy. He presents data from the ZIRCON study, and discusses the potential integration of AI in biomarker detection.

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High Resolution Micro-Ultrasound: Going Beyond MRI

Laurence Klotz, MD, FRCSC, illustrates the value of high resolution micro-ultrasound over that of multiparametric MRI (mpMRI) in prostate cancer staging and diagnosis. He begins by reviewing the history, strengths, and limitations of mpMRI, and he presents his own history with high resolution micro-ultrasound.

Dr. Klotz then explains the differences between high resolution micro-ultrasound and conventional ultrasound. He compares the sensitivity, precision, and accuracy of high resolution micro-ultrasound against those of mpMRI and conventional ultrasound.

Dr. Klotz concludes by examining the efficacy of combining mpMRI and high resolution micro-ultrasound for prostate cancer diagnosis and staging. He presents data from ongoing trials supporting the use of high resolution micro-ultrasound as a complement to mpMRI.

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