Jesse N. Mills, MD

Jesse N. Mills, MD

University of California Los Angeles

Los Angeles, California

Dr. Jesse N. Mills, MD, is a clinical professor of urology at the David Geffen School of Medicine at the University of California Los Angeles (UCLA). He is division chief of andrology, director of the Men’s Clinic at UCLA, fellowship director of the UCLA male reproductive medicine and surgery program, and director of UCLA Urology Santa Monica.

Dr. Mills is internationally recognized as a thought leader in male fertility, hypogonadism, erectile dysfunction, Peyronie's disease, and microsurgery. He has performed thousands of penile implants, vasectomy reversals, varicocelectomy and complex Peyronie's disease surgeries, and Xiaflex injections over the course of his career.

Dr. Mills completed his medical degree at the University of Iowa Hospitals and Clinics in 2001, followed by his residency at the University of Colorado Health Science Center in 2007. He then completed his fellowship at Baylor College of Medicine in 2008 and received his medical board certification in urology from the American Board of Urology in 2010. His clinical specialties revolve around men's health and include male hormone management, sexual and ejaculatory dysfunction, male fertility, and Peyronie's disease. He is also the author of the bestselling book A Field Guide to Men's Health.

Talks by Jesse N. Mills, MD

Update on Penile Implants: Best Practice and Taking Care of Complications

Update on Penile Implants: Best Practice and Taking Care of Complications

Posted by | Oct 2024

Jesse N. Mills, MD, delivers an insightful presentation on the latest advancements and best practices in using penile implants.

In this 14-minute discussion, Dr. Mills reviews prep and surgical techniques. He also discusses both early and late complications associated with penile implants and outlines strategies for addressing issues such as infection and erosion. He stresses the importance of patient follow-up to ensure early detection and management of complications, thereby improving long-term outcomes.

Dr. Mills concludes by emphasizing the need for continuous education and skill development among urologists to keep pace with advancements in penile implant technology and surgical techniques. His presentation is a comprehensive guide for clinicians seeking to enhance their practice in managing penile implants and caring for patients experiencing complications.

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The Immortal Field of Longevity in Men’s Health

The Immortal Field of Longevity in Men’s Health

Posted by | Aug 2024

Jesse N. Mills, MD, discusses longevity, an evolving field in men’s health. Dr. Mills begins by framing longevity within the broader context of men’s health, emphasizing that longevity is not merely about extending lifespan but enhancing the quality of life.
Dr. Mills explores the key factors contributing to longevity, including testosterone management, cardiovascular health, and mental well-being. He discusses many popular anti-aging therapies that, once only used by professional athletes, have become more common, such as saunas, cold plunges, and hyperbaric oxygen chambers. Moreover, Dr. Mills discusses pharmaceuticals that improve longevity, including semaglutides, metformin, and testosterone.
He also discusses the critical importance of cardiovascular health, noting that many of the same factors that contribute to heart disease—such as diet, exercise, and stress management—are also essential for promoting longevity. He also delves into the psychological aspects of longevity, arguing that addressing issues such as depression, anxiety, and social isolation is crucial.

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Deciphering Options for Testosterone Replacement Therapy and Managing Withdrawal

Deciphering Options for Testosterone Replacement Therapy and Managing Withdrawal

Posted by | Apr 2024

Jesse N. Mills, MD, discusses the importance of testosterone replacement therapy and presents an algorithm for determining treatment and managing withdrawal. He begins with an overview of the history of the study of testosterone, from the first recorded effects of castration to the warning against the over-prescription of testosterone therapy issued in 2015 by the FDA.

Dr. Mills discusses the AUA guidelines for testosterone replacement therapy and the lack of on-label options for treatment. He presents options for on-and-off-label testosterone replacement therapy.

Dr. Mills then presents an algorithm for determining the best treatment option for the patient, beginning by addressing male fertility concerns. He addresses questions of lab work, transference, insurance, administration, and other patient and physician concerns.

Dr. Mills concludes with the discontinuation of testosterone replacement therapy and when it is indicated. He discusses the available options for weaning patients off of testosterone, cautioning strongly against abrupt discontinuation.

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Managing the Man with Ejaculatory Dysfunction

Managing the Man with Ejaculatory Dysfunction

Posted by | Mar 2024

Jesse N. Mills, MD, presents management strategies for men presenting with ejaculatory dysfunctions, ranging from premature ejaculation to ejaculodynia. He begins by acknowledging that there is no current FDA-approved treatment specifically for any kind of ejaculatory dysfunction.

Dr. Mills then separates men presenting with ejaculatory dysfunction into distinct categories based on the symptom they are experiencing, and follow-up questions to ask these patients. These five main groups are Premature Ejaculation, Delayed Ejaculation, Anejaculation, Ejaculodynia, and Post-Orgasmic Illness Syndrome.

Throughout the presentation, Dr. Mills discusses each category of dysfunction and available treatment options. He concludes by highlighting the need for further study of post-orgasmic illness syndrome.

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In-office Therapies for Men with Erectile Dysfunction

In-office Therapies for Men with Erectile Dysfunction

Posted by | Mar 2024

Jesse N. Mills, MD, discusses the effectiveness of a selection of experimental in-office therapies for erectile dysfunction treatment. Throughout his presentation, Dr. Mills explores the outlook, benefits, and challenges of experimental therapy options currently pushed by external market forces, including:

Low-intensity Shockwave Therapy (LiSWT)
Platelet-Rich Plasma (PRP)
Stem Cell Therapy
Intracavernosal Injection (ICI)
Hyperbaric Oxygen

Dr. Mills concludes by stressing that although these therapy options are still considered experimental, urologists should strive to observe these therapies and hold balanced conversations with patients regarding their efficacy. He encourages urologists to stay optimistic about erectile dysfunction treatment as stewards of male health, suggesting they watch for new data in the world of experimental treatments.

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