Changing Distribution, Size and Grade of Prostate Cancer: Whole-Mount Prostatectomy Analysis

by M. Scott Lucia, MD | Jul 2018

M. Scott Lucia, MD, presented “Changing Distribution, Size and Grade of Prostate Cancer: Whole-Mount Prostatectomy Analysis” during the 23rd Annual Southwest Prostate Cancer Update on April 15, 2018 in Scottsdale, Arizona


How to cite: Lucia, M. Scott. Changing Distribution, Size and Grade of Prostate Cancer: Whole-Mount Prostatectomy Analysis” April 15, 2018. Accessed [date today]. https://grandroundsinurology.com/changing-distribution-size-and-grade-of-prostate-cancer-whole-mount-prostatectomy-analysis/

Changing Distribution, Size and Grade of Prostate Cancer: Whole-Mount Prostatectomy Analysis – Summary:

M. Scott Lucia, MD, summarizes the changes in the clinical management of prostate cancer since 1990, specifically regarding PSA screening, active surveillance, targeted focal therapy, and pathology grading practices. Also, he analyzes whole-mount prostatectomy data from the past 16 years that has shown increasingly higher grade and volume tumors. He then discusses whether or not this is exclusively due to patient selection and over-grading.

ABOUT THE AUTHOR

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M. Scott Lucia, MD, is Professor of Anatomic Pathology, Vice Chair of the Department of Pathology, and Director of Pathology Shared Resource and Research Histology at the University of Colorado in Denver. (He also serves as the Director of the Prostate Cancer Research Laboratories at UCAMC and of the UCAMC Biorepository Core Facility.) Dr. Lucia’s specialities are anatomic and clinical pathology. His primary areas of interest include pathology of prostate cancer and hyperplasia, early detection and prevention of prostate cancer, prostate cancer biomarkers, and mechanisms of carcinogenesis.  

Dr. Lucia earned his medical degree from the University of Colorado. He completed his internship and residency in Pathology at the University of Colorado. Dr. Lucia then completed a research fellowship in the Laboratory of Chemoprevention at the National Cancer Institute in Rockville, Maryland. 

Dr. Lucia served as the primary pathologist for multiple clinical trials for prostate and bladder cancer including the Prostate Cancer Prevention Trial (PCPT) and Vitamin E and Selenium Chemoprevention Trial (SELECT), sponsored by the Southwest Oncology Group; the Medical Therapy of Prostatic Symptoms (MTOPS) trial, sponsored by the NIDDK; and the Reduction with Dutasteride of Clinical Progression Events in Expectant Management of Prostate Cancer (REDEEM), sponsored by GlaxoSmithKline. He directs the operation of several tissue and serum biorepositories for prostate and prostatic diseases, including those for the PCPT, MTOPS, SELECT, and the University of Colorado Cancer Center Biorepository. He has authored or co-authored over 230 peer-reviewed articles, reviews, editorials, and book chapters.