Topic: BPH

TURP in 2024

Granville L. Lloyd, MD, provides a comprehensive overview of therapies for benign prostatic hyperplasia (BPH), focusing on the evolution from medical to procedural interventions. In this 9-minute presentation, he highlights the ongoing development and competition among various technologies, emphasizing procedural therapy over medical management in terms of sexual outcomes. Dr. Lloyd’s presentation describes the wide array of procedural options, including TURP, Rezūm, UroLift, and newer approaches like Optilume.

The economic and clinical burden of BPH is underscored. Dr. Lloyd advocates for a personalized approach to selecting the appropriate therapy, utilizing the best tool available for each patient while acknowledging the evolving role of newer technologies.

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HoLEP

Lori B. Lerner, MD, delves into the complexities of enucleation techniques for treating benign prostatic hyperplasia (BPH), emphasizing the importance of understanding prostate anatomy. In this 11-minute presentation, she highlights how individual anatomical variations influence surgical decisions and outcomes, particularly in laser enucleation.

Dr. Lerner outlines different approaches to enucleation, involving strategic incisions to address each patient’s specific anatomy. She discusses complex cases, such as patients with a significant portion of their prostate extending into the bladder, nodular prostates, or elevated bladder necks, which necessitate tailored approaches.

Dr. Lerner’s presentation underscores the necessity of careful preoperative imaging, using tools like MRI or CAT scans, to map the prostate’s structure and guide the surgical approach. She advocates against routine excessive testing, emphasizing responsible and targeted use of diagnostic tools to inform clinical decisions without unnecessary expenditure. Lerner also addresses potential complications such as postoperative stress urinary incontinence.

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BPH Morcellation

Amy E. Kramback, MD, presents a detailed overview of morcellation and its potential complications, particularly in Holmium Laser Enucleation of the Prostate (HoLEP). In this 14-minute presentation, she explains the technical requirements for performing morcellation.

Dr. Rebeck narrates a video of the procedure’s steps. She highlights how challenging nodules can sometimes require additional laser grooves to enable effective morcellation.

Complications during morcellation are also reviewed. Intraoperative issues include capsular perforations and bladder injuries. Injury to the ureteral orifices, while rare, can occur during morcellation. Dr. Krambeck also discusses postoperative complications and their management, including bleeding, clot retention, and infections such as UTIs or epididymitis. Incontinence, mainly urge incontinence, is another common postoperative issue. However, with proper technique, HoLEP and morcellation present low complication rates and excellent patient outcomes.

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Optilume

Garrett D. Pohlman, MD, discusses the Optilume BPH procedure, a novel treatment for benign prostatic hyperplasia (BPH). In this 11-minute talk, Pullman gives step-by-step instructions for the Optilume placement procedure, emphasizing how the treatment can be tailored to individual patients based on prostate size, anatomy, and personal preferences.

Pullman discusses the safety and efficacy of Optilume, as well as data from studies like Pinnacle and Everest. He also shares that the placement procedure can be performed in various settings, including outpatient surgery centers and offices. He asserts that Optilume BPH is a promising, durable, and patient-friendly option for treating BPH.

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Should MIST be First Line Treatment for BPH?

Seth K. Bechis, MD, explores the question of whether or not minimally invasive surgical therapies (MIST) should be first line treatment for BPH. He begins by highlighting the prevalence of BPH in men over 60. He acknowledges that combination therapy is extremely effective in combating BPH in the short-term, but it has several long-term risks which impact patient QoL.

Dr. Bechis highlights the negative side-effects of 5-ARIs, alpha blockers, and surgery post-medication-failure. Side-effects included increased risk of cardiac failure, dementia, depression, and sexual dysfunction.

Dr. Bechis then examines current MIST procedures for BPH treatment, including prostatic urethral lifts, water vapor thermal therapy, temporarily implanted nitinol devices, and balloons. He examines the durability, effectiveness, and side-effects for each procedure, and compares them to patients on medication

Dr. Bechis concludes by comparing the cost effectiveness of MIST procedures to the cost of medication, taking into account IPSS improvement and Quality-Adjusted Life Years over time. Overall, he suggests that MIST procedures should be explored as a first line treatment for BPH.

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The Prostatic Urethral Lift (Urolift): Back to Basics

Matthew C. Ercolani, MD, FACS, provides an overview of UroLift, a minimally invasive procedure for benign prostatic hyperplasia (BPH). In this 11-minute presentation, Ercolani explains his reasoning for performing the UroLift procedure and its benefits compared to other options.

Dr. Ercolani reviews the optimal patient profile, best placement locations, and areas to avoid when performing the implant procedure. He then shares a video of implantation, illustrating how to customize Urolift placement and providing a “before and after” comparison.

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Rezum, Stents

Kevin C. Zorn, MD, FACS, FRCSC, addresses the challenges and advancements in managing benign prostatic hyperplasia (BPH), focusing on minimally invasive surgical techniques. In this 17-minute presentation, he highlights the limitations of traditional treatments, such as transurethral resection of the prostate (TURP), and a growing demand for effective and less invasive alternative options.

Dr. Zorn explores the evolution of BPH treatments, discussing the importance of finding office-based, quick, and cost-effective solutions. He describes various less invasive technologies, including UroLift, Rezūm, and novel stent devices like iTind and Optilume.

Zorn underscores the variability in patient outcomes based on prostate anatomy and tissue composition, noting the importance of personalized treatment approaches. Moving towards a more tailored approach, similar to the precision seen in prostate cancer management, considers prostate size and tissue composition.

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Laser Selection for HoLEP

Pierluigi Bove, MD, discusses the selection of lasers for Holmium laser enucleation of the prostate (HoLEP), focusing on the evolution and advancements in laser technology since 1995. In this 9-minute presentation, Bove emphasizes that the choice of laser depends on personal preference and experience, technical features, and economic considerations. Dr. Bove considers the Holmium laser the gold standard for BPH surgery due to its versatility in treating various prostate sizes and conditions such as stones.

The discussion then shifts to a comparison between the traditional Holmium laser and newer technologies like the Thulium laser with pulse modulation. Bove presents evidence suggesting that the MOSES effect, available with Holmium lasers, can improve intraoperative hemostasis, shorten operative time, and enhance outcomes.

Ultimately, the selection of the appropriate laser for prostate enucleation depends on various factors, including the surgeon’s familiarity with the technology, the type of procedure, and resource availability.

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Greenlight PVP

Gregg R. Eure, MD, FACS, outlines the use of GreenLight laser therapy in urology, focusing on its advantages and technique. In this 8-minute presentation, he shares that this laser therapy is efficient, with treatments often lasting under an hour and offering quicker recovery compared to transurethral resection of the prostate (TURP).

Dr. Eure shares that the GreenLight laser is ideal for underwater procedures, comparing it to different laser types, such as thulium and holmium lasers, which are primarily used for stone treatment. He concludes the presentation with practical tips, including managing anticoagulated patients, avoiding use in radiated tissue, and suggestions for patient counseling regarding postoperative expectations.

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Optimizing BPH Clinical Pathway: Navigating the Next 20 Years

Ilya Sobol, MD provides a forward-looking analysis on optimizing the clinical pathway for benign prostatic hyperplasia (BPH) over the next 20 years. He emphasizes the integration of emerging technologies, personalized medicine, and patient-centered care to enhance treatment outcomes and patient satisfaction.

Dr. Sobol discusses the evolving landscape of BPH management, highlighting advances in diagnostic tools, such as improved imaging techniques and biomarker identification, and minimally invasive therapies, such as transurethral water jet ablation and laser enucleation, should be incorporated into standard practice.

Telemedicine and digital health technologies are highlighted as key components of the future clinical pathway. Dr. Sobol envisions the integration of telehealth services for routine follow-ups and monitoring. He also advocates for comprehensive patient education programs that empower individuals to make informed decisions about their care.

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Practical Considerations of Laser Enucleation Programs

Ilya Sobol, MD, provides an in-depth analysis of the practical considerations involved in implementing and managing laser enucleation programs for benign prostatic hyperplasia (BPH). His discussion focuses on the technical aspects, patient selection, and logistical requirements essential for the successful execution of these programs.

Dr. Sobol outlines the advantages of laser enucleation techniques, such as holmium laser enucleation of the prostate (HoLEP). Dr. Sobol also discusses the technical expertise required for performing laser enucleation. He highlights the necessity for specialized training and experience to master the technique. Logistical considerations are also addressed, including the need for appropriate facilities and equipment.

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Overview of Current Surgical BPH

Amy Krambeck, MD, provides a comprehensive overview of current surgical options for treating benign prostatic hyperplasia (BPH), focusing on their efficacy, safety, and practical application. Her analysis emphasizes the evolution of surgical techniques and the criteria for selecting the most appropriate intervention for each patient.

Dr. Krambeck begins by discussing transurethral resection of the prostate (TURP), noting its potential complications, such as bleeding, infection, and the risk of TUR syndrome, which necessitates careful patient selection and postoperative monitoring. She then explores newer surgical techniques as alternatives to TURP, among these, laser therapies such as holmium laser enucleation of the prostate (HoLEP) and photoselective vaporization of the prostate (PVP). Dr. Krambeck also addresses minimally invasive surgical options like prostatic urethral lift (PUL) and water vapor thermal therapy.

The discussion includes a review of the practical considerations for each surgical option, including patient factors such as prostate size, comorbidities, and symptom severity. Complications and postoperative care are also discussed.

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