Nelson N. Stone, MD, presented “Can One Biopsy Event Determine Type and Amount of Focal Therapy Treatment?​” during the Southwest Prostate Cancer Symposium 2020 virtual conference in December 2020.

How to cite: Stone, Nelson N. Can One Biopsy Event Determine Type and Amount of Focal Therapy Treatment?” December 2020. Accessed Sep 2021. https://grandroundsinurology.com/can-one-biopsy-event-determine-type-and-amount-of-treatment/

Can One Biopsy Event Determine Type and Amount of Focal Therapy Treatment? – Summary

Nelson N. Stone, MD, Professor of Urology, Radiation Oncology, and Oncological Sciences at the Icahn School of Medicine at Mount Sinai and at the Derald H. Ruttenberg Cancer Center at Mount Sinai, argues for the use of transperineal mapping biopsy (TPMB), and against the use of strict criteria and cursory cancer identification methods for finding focal therapy-eligible patients. He expresses a clinical need for a process that identifies focal therapy candidates and lists which portions of the prostate require treatment, and suggests that TPMB can fulfill these goals. Dr. Stone summarizes a review of the evidence for using focal therapy for the treatment of prostate cancer and found that despite at least 50% of patients being focal therapy-eligible, only a minority of patients actually receive the therapy. He also critiques a study on focal therapy eligibility determined by MRI/US fusion biopsy on the basis of using too strict of criteria for selecting patients and in consideration of the possibility of missing many patients due to not using a biopsy. Dr. Stone discusses several other studies that depict MRI as unreliable in accurately identifying focal therapy patients compared to TPMP due to the lower accuracy of MRI across the prostate.

About the Southwest Prostate Cancer Symposium 2020 virtual conference:
Presented by Program Chairs Nelson N. Stone, MD, and Richard G. Stock, MD, this virtual conference educated attendees about advances in the management of localized and advanced prostate cancer, with a focus on imaging, technology, and training in the related devices. It included a scientific session, as well as live demonstrations of surgical techniques. You can learn more about the conference, including the 2021 iteration, here.