Evolving Intersection Between Inherited Cancer Genetics and Therapeutic Clinical Trials in Prostate Cancer

Neil F. Mariados, MD, describes the role of genetic mutations in the efficacy of prostate cancer treatment options and in the science behind poly (ADP-ribose) polymerase (PARP) inhibition. He also reviews clinical trials leading to PARP inhibitor research in prostate cancer and the many clinical trials investigating the intersection between cancer genetics and prostate cancer.

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