Topic: Prostate Cancer

The Role of FSH in Prostate Cancer

Marc B. Garnick, MD, addresses the question, “Does Follicle Stimulating Hormone (FSH) effect prostate cancer progression and adverse effects to androgen deprivation therapy (ADT), and should we be modulating it?” He presents evidence for both the pro and con sides of this argument.

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Updates on the ERSPC and the PLCO Trials

Dr. Gerald L. Andriole, MD, reviews the designs, materials, and outcomes of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) and The European Randomized Study of Screening for Prostate Cancer (ERSPC). He distinguishes between legitimate concerns and inappropriate criticisms of the trials. Also, he explains what this means for the practice of PSA testing.

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The Evolution of Understanding the USPSTF: Recommendations and Controversy

Dr. Neal Shore, MD, FACS, stands in for Deepak A. Kapoor, MD, at the 28th International Prostate Cancer Update, summarizing the history of the United States Preventive Services Task Force (USPSTF) and their Recommendation Grades for disease prevention and screening services. He explains the issues that arise when lawmakers attempt to use USPSTF recommendations as a basis for insurance laws. Specifically, he explains how healthcare policy effects PSA testing.

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The Burden of Prostate Cancer Today and in the Future

In this presentation, Dr. Patrick Walsh expands upon Dr. Veda N. Giri’s introduction to the Philadelphia Prostate Cancer Consensus 2017. While she set forth the goals of the meeting and emphasized the importance of drafting centralized guidelines for genetic testing, Dr. Walsh focuses on PSA testing. He summarizes the past of PSA testing to give context to the urological community’s goals for the future.

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An Overview of MRI Guided Biopsies for Prostate Cancer

Robert Abouassaly, MD, argues that the DECIPHER marker is not an ideal test for predicting patient’s response to chemotherapy. He cites the inconclusiveness of trials and research and the cost inefficiency of this biomarker. Also, he explains that the DECIPHER test’s classification system is based on RNA expression profiles, and not meant for therapeutic guidance. This is a counter argument to Alan H. Bryce’s lecture, “The DECIPHER Marker Can Predict Chemotherapy.” 

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